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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NMDAR2C/GRIN2C Antibody Picoband®

SKU : BHA21000277

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Mfr.No.	PB9374, PB9374-10ug, PB9374-Biotin, PB9374-Cy3, PB9374-Dylight488, PB9374-Dylight550, PB9374-Dylight594, PB9374-FITC, PB9374-HRP, PB9374-APC, PB9374-PE, PB9374-iFluor647, PB9374-carrier-free
Alternative Names	Glutamate receptor ionotropic, NMDA 2C
Background	NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate (NMDA) receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as leaing, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-NMDAR2C/GRIN2C Antibody Picoband® catalog # PB9374. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
Host	Rabbit
Immunogen Region	E.coli-derived human NMDAR2C recombinant protein (Position: Q43-Q242). Human NMDAR2C shares 93% and 92.5% amino acid (aa) sequence identity with mouse and rat NMDAR2C, respectively.
Isotype	Rabbit IgG
Molecular Weight	134 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Glutamate receptor ionotropic, NMDA 2C;GluN2C;Glutamate (NMDA) receptor subunit epsilon-3;N-methyl D-aspartate receptor subtype 2C;NMDAR2C;NR2C;GRIN2C;NMDAR2C;
Tissue Specificity	Mainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q14957
Gene Id	2905
Gene Name	GRIN2C
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Rat, Human

Reference	1. Kalsi G, Whiting P, Bourdelles BL, Callen D, Baard EA, Gurling H (Apr 1998). "Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels". Genomics47 (3): 4235. doi:10.1006/geno.1997.5132.PMID 9480759. 2. "Entrez Gene: GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C".

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000277-1	PB9374	100 ug	-	$370		Add to Cart
BHA21000277-2	PB9374-10ug	10 ug	Sample	$99		Add to Cart
BHA21000277-3	PB9374-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000277-4	PB9374-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000277-5	PB9374-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000277-6	PB9374-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000277-7	PB9374-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000277-8	PB9374-FITC	100 ug	FITC	$570		Add to Cart
BHA21000277-9	PB9374-HRP	100 ug	HRP	$570		Add to Cart
BHA21000277-10	PB9374-APC	100 ug	APC	$670		Add to Cart
BHA21000277-11	PB9374-PE	100 ug	PE	$670		Add to Cart
BHA21000277-12	PB9374-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000277-13	PB9374-carrier-free	100 ug	carrier-free	$370		Add to Cart

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