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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NMDAR2B/GRIN2B Antibody Picoband®

SKU : BHA21006643

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Mfr.No.	PA1059, PA1059-10ug, PA1059-Biotin, PA1059-Cy3, PA1059-Dylight488, PA1059-Dylight550, PA1059-Dylight594, PA1059-FITC, PA1059-HRP, PA1059-APC, PA1059-PE, PA1059-iFluor647, PA1059-carrier-free
Alternative Names	Glutamate receptor ionotropic, NMDA 2B
Background	The N-methyl-D-aspartate receptor 2B, also names as GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98% and 96% identical to the sequences of the rat and mouse Nmdar2b proteins, respectively. Nmdar2B gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12 overexpression of NMDA receptor 2B (NR2B) in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-NMDAR2B/GRIN2B Antibody catalog # PA1059. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosp
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human NMDAR2B, identical to the related mouse and rat sequence.
Isotype	Rabbit IgG
Molecular Weight	30 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Glutamate receptor ionotropic, NMDA 2B;GluN2B;Glutamate (NMDA) receptor subunit epsilon-2;N-methyl D-aspartate receptor subtype 2B;NMDAR2B;NR2B;N-methyl-D-aspartate receptor subunit 3;NR3;hNR3;GRIN2B;NMDAR2B;
Tissue Specificity	Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q13224
Gene Name	GRIN2B
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat, Human<br>

Reference	1. Mandich, P.; Schito, A. M.; Bellone, E.; Antonacci, R.; Finelli, P.; Rocchi, M.; Ajmar, F. : Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12. Genomics 22: 216-218, 1994. <br /><br />2. Tang, Y.-P.; Shimizu, E.; Dube, G. R.; Rampon, C.; Kerchner, G. A.; Zhuo, M.; Liu, G.; Tsien, J. Z. : Genetic enhancement of leaing and memory in mice. Nature 401: 63-69, 1999.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006643-1	PA1059	-	100 ug	$370		Add to Cart
BHA21006643-2	PA1059-10ug	Sample	10 ug	$99		Add to Cart
BHA21006643-3	PA1059-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006643-4	PA1059-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006643-5	PA1059-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006643-6	PA1059-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006643-7	PA1059-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006643-8	PA1059-FITC	FITC	100 ug	$570		Add to Cart
BHA21006643-9	PA1059-HRP	HRP	100 ug	$570		Add to Cart
BHA21006643-10	PA1059-APC	APC	100 ug	$670		Add to Cart
BHA21006643-11	PA1059-PE	PE	100 ug	$670		Add to Cart
BHA21006643-12	PA1059-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006643-13	PA1059-carrier-free	carrier-free	100 ug	$370		Add to Cart

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