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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NMDAR2A/GRIN2A Antibody Picoband®

SKU : BHA21000233

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Mfr.No.	PB9335, PB9335-10ug, PB9335-Biotin, PB9335-Cy3, PB9335-Dylight488, PB9335-Dylight550, PB9335-Dylight594, PB9335-FITC, PB9335-HRP, PB9335-APC, PB9335-PE, PB9335-iFluor647, PB9335-carrier-free
Alternative Names	Glutamate receptor ionotropic, NMDA 2A
Background	GRIN2A is also known as N-methyl-D-aspartate receptor channel, subunit epsilon-1 (NMDAR2A). This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-NMDAR2A/GRIN2A Antibody Picoband® catalog # PB9335. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
Host	Rabbit
Immunogen Region	E.coli-derived human NMDAR2A recombinant protein (Position: D958-R1300). Human NMDAR2A shares 89% and 90% amino acid (aa) sequence identity with mouse and rat NMDAR2A, respectively.
Isotype	Rabbit IgG
Molecular Weight	165 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Glutamate receptor ionotropic, NMDA 2A;GluN2A;Glutamate (NMDA) receptor subunit epsilon-1;N-methyl D-aspartate receptor subtype 2A;NMDAR2A;NR2A;hNR2A;GRIN2A;NMDAR2A;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q12879
Gene Id	2903
Gene Name	GRIN2A
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Western blot, 0.1-0.5ug/ml, Mouse, Rat, Human

Reference	1. Kalsi, G.; Whiting, P.; Le Bourdelles, B.; Callen, D.; Barnard, E. A.; Gurling, H. : Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels. Genomics 47: 423-425, 1998. 2. Micu, I.; Jiang, Q.; Coderre, E.; Ridsdale, A.; Zhang, L.; Woulfe, J.; Yin, X.; Trapp, B. D.; McRory, J. E.; Rehak, R.; Zamponi, G. W.; Wang, W.; Stys, P. K. : NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature 439: 988-992, 2006.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000233-1	PB9335	100 ug	-	$370		Add to Cart
BHA21000233-2	PB9335-10ug	10 ug	Sample	$99		Add to Cart
BHA21000233-3	PB9335-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000233-4	PB9335-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000233-5	PB9335-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000233-6	PB9335-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000233-7	PB9335-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000233-8	PB9335-FITC	100 ug	FITC	$570		Add to Cart
BHA21000233-9	PB9335-HRP	100 ug	HRP	$570		Add to Cart
BHA21000233-10	PB9335-APC	100 ug	APC	$670		Add to Cart
BHA21000233-11	PB9335-PE	100 ug	PE	$670		Add to Cart
BHA21000233-12	PB9335-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000233-13	PB9335-carrier-free	100 ug	carrier-free	$370		Add to Cart

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