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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NLRP2 Antibody Picoband®

SKU : BHA21006382

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Mfr.No.	A04819-3, A04819-3-10ug, A04819-3-Biotin, A04819-3-Cy3, A04819-3-Dylight488, A04819-3-Dylight550, A04819-3-Dylight594, A04819-3-FITC, A04819-3-HRP, A04819-3-APC, A04819-3-PE, A04819-3-iFluor647, A04819-3-carrier-free
Background	NACHT, LRR and PYD domains-containing protein 2 is a protein that in humans is encoded by the NLRP2 gene. This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alteative splicing results in multiple transcript variants encoding different isoforms.
Clonality	Polyclonal
Description	Boster Bio Anti-NLRP2 Antibody Picoband® catalog # A04819-3. Tested in WB, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	E.coli-derived human NLRP2 recombinant protein (Position: H80-D1044).
Molecular Weight	121 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9NX02
Gene Id	55655
Gene Name	NLRP2

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	ELISA, Flow Cytometry, IP, IF, ICC, WB
Description	Weste blot, 0.25-0.5 ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Immunoprecipitation, 0.5-2 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Agostini, L., Martinon, F., Bus, K., McDermott, M. F., Hawkins, P. N., Tschopp, J. NALP3 forms an IL-1-beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20: 319-325, 2004. 2. Bruey, J. M., Bruey-Sedano, N., Newman, R., Chandler, S., Stehlik, C., Reed, J. C. PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappa-B and caspase-1 activation in macrophages. J. Biol. Chem. 279: 51897-51907, 2004. 3. Kuchmiy, A. A., D'Hont, J., Hochepied, T., Lamkanfi, M. NLRP2 controls age-associated mateal fertility. J. Exp. Med. 213: 2851-2860, 2016.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006382-1	A04819-3	-	100 ug	$370		Add to Cart
BHA21006382-2	A04819-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21006382-3	A04819-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006382-4	A04819-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006382-5	A04819-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006382-6	A04819-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006382-7	A04819-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006382-8	A04819-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21006382-9	A04819-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21006382-10	A04819-3-APC	APC	100 ug	$670		Add to Cart
BHA21006382-11	A04819-3-PE	PE	100 ug	$670		Add to Cart
BHA21006382-12	A04819-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006382-13	A04819-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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