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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NFkB/NFKB1 p105/p50 Antibody Picoband®

SKU : BHA21007315

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Mfr.No.	PA2111, PA2111-10ug, PA2111-Biotin, PA2111-Cy3, PA2111-Dylight488, PA2111-Dylight550, PA2111-Dylight594, PA2111-FITC, PA2111-HRP, PA2111-APC, PA2111-PE, PA2111-iFluor647, PA2111-carrier-free
Alternative Names	Nuclear factor NF-kappa-B p105 subunit
Background	Nuclear factor NF-kappa-B p105 subunit, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-NFkB/NFKB1 p105/p50 Antibody catalog # PA2111. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immuni
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of mouse NFkB/NFKB1 p105/p50, identical to the related rat sequence, and different from the related human sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	105 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Nuclear factor NF-kappa-B p105 subunit;DNA-binding factor KBF1;EBP-1;NF-kappa-B1 p84/NF-kappa-B1 p98;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1;Nuclear factor NF-kappa-B p50 subunit;Nfkb1;
Tissue Specificity	Major component of lens fiber gap junctions.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P25799
Gene Name	NFKB1
Sequence	Contains 7 ANK repeats.
Subcellular Location	Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1. Adler, A. S., Sinha, S., Kawahara, T. L. A., Zhang, J. Y., Segal, E., Chang, H. Y. Motif module map reveals enforcement of aging by continual NF-kappa-beta activity. Genes Dev. 21: 3244-3257, 2007.<br /><br />2. Baek, S. H., Ohgi, K. A., Rose, D. W., Koo, E. H., Glass, C. K., Rosenfeld, M. G. Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappa-B and beta-amyloid precursor protein. Cell 110: 55-67, 2002.<br /><br />3. Huxford, T., Huang, D.-B., Malex, S., Ghosh, G. The crystal structure of the I-kappa-B-alpha complex reveals mechanisms of NF-kappa-B inactivation. Cell 95: 759-770, 1998.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007315-1	PA2111	-	100 ug	$370		Add to Cart
BHA21007315-2	PA2111-10ug	Sample	10 ug	$99		Add to Cart
BHA21007315-3	PA2111-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007315-4	PA2111-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007315-5	PA2111-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007315-6	PA2111-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007315-7	PA2111-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007315-8	PA2111-FITC	FITC	100 ug	$570		Add to Cart
BHA21007315-9	PA2111-HRP	HRP	100 ug	$570		Add to Cart
BHA21007315-10	PA2111-APC	APC	100 ug	$670		Add to Cart
BHA21007315-11	PA2111-PE	PE	100 ug	$670		Add to Cart
BHA21007315-12	PA2111-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007315-13	PA2111-carrier-free	carrier-free	100 ug	$370		Add to Cart

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