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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NeuN/Rbfox3 Antibody Picoband®

SKU : BHA21004058

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Mfr.No.	A11954-1, A11954-1-10ug, A11954-1-Biotin, A11954-1-Cy3, A11954-1-Dylight488, A11954-1-Dylight550, A11954-1-Dylight594, A11954-1-FITC, A11954-1-HRP, A11954-1-APC, A11954-1-PE, A11954-1-iFluor647, A11954-1-carrier-free
Alternative Names	solute carrier family 2 member 6
Background	RNA binding protein, fox-1 homolog (C. elegans) 3 (Rbfox3) is a protein that in humans is encoded by the RBFOX3 gene. This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alteative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alteative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-NeuN/Rbfox3 Antibody Picoband® catalog # A11954-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Facilitative glucose transporter; binds cytochalasin B with low affinity.
Host	Rabbit
Immunogen Region	E.coli-derived mouse NeuN/Rbfox3 recombinant protein (Position: H28-D304).
Isotype	Rabbit IgG
Molecular Weight	46-55 kDa
Reactivity	Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9
Tissue Specificity	Highly expressed in brain, spleen and peripheral blood leukocytes.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q8BIF2
Gene Id	52897
Gene Name	Rbfox3
Subcellular Location	Cell membrane. Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	ELISA, IF, IHC, WB
Description	Weste blot, 0.1-0.25 ug/ml, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Mouse, Rat<br> Immunofluorescence, 5 ug/ml, Rat<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Dredge, B. K., Jensen, K. B. NeuN/Rbfox3 nuclear and cytoplasmic isoforms differentially regulate alteative splicing and nonsense-mediated decay of Rbfox2. PLoS One 6: e21585, 2011. Note: Electronic Article. <br /><br />2. Hartz, P. A. Personal Communication. Baltimore, Md. 6/22/2016.<br /><br />3. Kim, K. K., Adelstein, R. S., Kawamoto, S. Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors. J. Biol. Chem. 284: 31052-31061, 2009.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004058-1	A11954-1	-	100 ug	$370		Add to Cart
BHA21004058-2	A11954-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21004058-3	A11954-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004058-4	A11954-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004058-5	A11954-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004058-6	A11954-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004058-7	A11954-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004058-8	A11954-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21004058-9	A11954-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21004058-10	A11954-1-APC	APC	100 ug	$670		Add to Cart
BHA21004058-11	A11954-1-PE	PE	100 ug	$670		Add to Cart
BHA21004058-12	A11954-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004058-13	A11954-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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