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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NEIL3 Antibody Picoband®

SKU : BHA21005355

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Mfr.No.	A05497-4, A05497-4-10ug, A05497-4-Biotin, A05497-4-Cy3, A05497-4-Dylight488, A05497-4-Dylight550, A05497-4-Dylight594, A05497-4-FITC, A05497-4-HRP, A05497-4-APC, A05497-4-PE, A05497-4-iFluor647, A05497-4-carrier-free
Alternative Names	atypical chemokine receptor 2
Background	Nei endonuclease VIII-like 3 (E. coli) is a protein in humans that is encoded by the NEIL3 gene. NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-NEIL3 Antibody Picoband® catalog # A05497-4. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transc
Host	Rabbit
Immunogen Region	E.coli-derived human NEIL3 recombinant protein (Position: K244-K585).
Isotype	Rabbit IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Atypical chemokine receptor 2; C-C chemokine receptor D6; Chemokine receptor CCR-10; Chemokine receptor CCR-9; Chemokine-binding protein 2; Chemokine-binding protein D6; ACKR2; CCBP2; CCR10; CMKBR9; D6
Tissue Specificity	Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors. Expressed at high levels in Kaposi sarcoma-related pathologies. Expressed on apoptotic neutrophils (at protein level). Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q8TAT5
Gene Id	55247
Gene Name	NEIL3
Subcellular Location	Cell membrane. Multi-pass membrane protein. Early endosome. Recycling endosome

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, IHC, ELISA
Description	Western blot, 0.1-0.25 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Bandaru, V., Sunkara, S., Wallace, S. S., Bond, J. P. A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII. DNA Repair 1: 517-529, 2002.<br /><br />2. Morland, I., Rolseth, V., Luna, L., Rognes, T., Bjoras, M., Seeberg, E. Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA. Nucleic Acids Res. 30: 4926-4936, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005355-1	A05497-4	-	100 ug	$370		Add to Cart
BHA21005355-2	A05497-4-10ug	Sample	10 ug	$99		Add to Cart
BHA21005355-3	A05497-4-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005355-4	A05497-4-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005355-5	A05497-4-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005355-6	A05497-4-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005355-7	A05497-4-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005355-8	A05497-4-FITC	FITC	100 ug	$570		Add to Cart
BHA21005355-9	A05497-4-HRP	HRP	100 ug	$570		Add to Cart
BHA21005355-10	A05497-4-APC	APC	100 ug	$670		Add to Cart
BHA21005355-11	A05497-4-PE	PE	100 ug	$670		Add to Cart
BHA21005355-12	A05497-4-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005355-13	A05497-4-carrier-free	carrier-free	100 ug	$370		Add to Cart

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