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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NDUFS2 Antibody Picoband®

SKU : BHA21004395

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Mfr.No.	A05618-3, A05618-3-10ug, A05618-3-Biotin, A05618-3-Cy3, A05618-3-Dylight488, A05618-3-Dylight550, A05618-3-Dylight594, A05618-3-FITC, A05618-3-HRP, A05618-3-APC, A05618-3-PE, A05618-3-iFluor647, A05618-3-carrier-free
Alternative Names	JunD proto-oncogene, AP-1 transcription factor subunit
Background	NADH dehydrogenase (ubiquinone) iron-sulfur protein 2, mitochondrial (NDUFS2) also known as NADH-ubiquinone oxidoreductase 49 kDa subunit is an enzyme that in humans is encoded by the NDUFS2 gene. The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alteatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-NDUFS2 Antibody Picoband® catalog # A05618-3. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcription factor binding AP-1 sites.
Host	Rabbit
Immunogen Region	E.coli-derived human NDUFS2 recombinant protein (Position: M1-R463).
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Transcription factor jun-D; JUND
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	O75306
Gene Id	4720
Gene Name	NDUFS2
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Mouse<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Immunofluorescence, 5 ug/ml, Human, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10^6 cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Carilla-Latorre, S., Gallardo, M. E., Annesley, S. J., Calvo-Garrido, J., Grana, O., Accari, S. L., Smith, P. K., Valencia, A., Garesse, R., Fisher, P. R., Escalante, R. MidA is a putative methyltransferase that is required for mitochondrial complex I function. J. Cell Sci. 123: 1674-1683, 2010.<br /><br />2. Loeffen, J., Elpeleg, O., Smeitink, J., Smeets, R., Stockler-Ipsiroglu, S., Mandel, H., Sengers, R., Trijbels, F., van den Heuvel, L. Mutations in the complex I NDUFS2 gene of patients with cardiomyopathy and encephalomyopathy. Ann. Neurol. 49: 195-201, 2001. <br /><br />3. Loeffen, J., van den Heuvel, L., Smeets, R., Triepels, R., Sengers, R., Trijbels, F., Smeitink, J. cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed. Biochem. Biophys. Res. Commun. 247: 751-758, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004395-1	A05618-3	-	100 ug	$370		Add to Cart
BHA21004395-2	A05618-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21004395-3	A05618-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004395-4	A05618-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004395-5	A05618-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004395-6	A05618-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004395-7	A05618-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004395-8	A05618-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21004395-9	A05618-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21004395-10	A05618-3-APC	APC	100 ug	$670		Add to Cart
BHA21004395-11	A05618-3-PE	PE	100 ug	$670		Add to Cart
BHA21004395-12	A05618-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004395-13	A05618-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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