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Home / Primary Antibodies / Polyclonal Antibodies

Anti-N myc interactor/NMI Antibody Picoband®

SKU : BHA21000238

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Mfr.No.	PB9340, PB9340-10ug, PB9340-Biotin, PB9340-Cy3, PB9340-Dylight488, PB9340-Dylight550, PB9340-Dylight594, PB9340-FITC, PB9340-HRP, PB9340-APC, PB9340-PE, PB9340-iFluor647, PB9340-carrier-free
Alternative Names	N-myc-interactor
Background	NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-N myc interactor/NMI Antibody Picoband® catalog # PB9340. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5.
Host	Rabbit
Immunogen Region	E.coli-derived human NMI recombinant protein (Position: E2-E307). Human NMI shares 64% amino acid (aa) sequence identity with mouse NMI.
Isotype	Rabbit IgG
Molecular Weight	35 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	N-myc-interactor;Nmi;N-myc and STAT interactor;NMI;
Tissue Specificity	Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q13287
Gene Id	9111
Gene Name	NMI
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Immunocytochemistry/Immunofluorescence, 2ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. Albihn A, et al. Camptothecin-induced apoptosis is enhanced by Myc and involves PKCdelta signaling. Int J Cancer, 2007 Oct 15. 2. Fillmore RA, et al. Nmi (N-Myc interactor) inhibits Wnt/beta-catenin signaling and retards tumor growth. Int J Cancer, 2009 Aug 1. 3. Lebrun SJ, et al. Interferon-induced upregulation and cytoplasmic localization of Myc-interacting protein Nmi. J Interferon Cytokine Res, 1998 Sep.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000238-1	PB9340	100 ug	-	$370		Add to Cart
BHA21000238-2	PB9340-10ug	10 ug	Sample	$99		Add to Cart
BHA21000238-3	PB9340-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000238-4	PB9340-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000238-5	PB9340-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000238-6	PB9340-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000238-7	PB9340-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000238-8	PB9340-FITC	100 ug	FITC	$570		Add to Cart
BHA21000238-9	PB9340-HRP	100 ug	HRP	$570		Add to Cart
BHA21000238-10	PB9340-APC	100 ug	APC	$670		Add to Cart
BHA21000238-11	PB9340-PE	100 ug	PE	$670		Add to Cart
BHA21000238-12	PB9340-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000238-13	PB9340-carrier-free	100 ug	carrier-free	$370		Add to Cart

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