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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MYH16 Antibody Picoband®

SKU : BHA21005593

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Mfr.No.	A15498, A15498-10ug, A15498-Biotin, A15498-Cy3, A15498-Dylight488, A15498-Dylight550, A15498-Dylight594, A15498-FITC, A15498-HRP, A15498-APC, A15498-PE, A15498-iFluor647, A15498-carrier-free
Alternative Names	kelch repeat and BTB domain containing 2
Background	The MYH16 gene, encoding a sarcomeric myosin heavy chain expressed in nonhuman primate masticatory muscles, is inactivated in humans. Stedman et al. (2004) hypothesized that the decrement in masticatory muscle size caused by the inactivation of MYH16 removed an evolutionary constraint on encephalization in early man.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MYH16 Antibody Picoband® catalog # A15498. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completio
Host	Rabbit
Immunogen Region	E.coli-derived human MYH16 recombinant protein (Position: K405-A1073).
Isotype	Rabbit IgG
Molecular Weight	128 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489
Tissue Specificity	Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9H6N6
Gene Id	84176
Gene Name	MYH16
Subcellular Location	Cul3-RING ubiquitin ligase complex.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	ELISA, IF, ICC, WB, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Desjardins, P. R., Burkman, J. M., Shrager, J. B., Allmond, L. A., Stedman, H. H. Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family. Molec. Biol. Evol. 19: 375-393, 2002.<br /><br />2. Stedman, H. H., Kozyak, B. W., Nelson, A., Thesier, D. M., Su, L. T., Low, D. W., Bridges, C. R., Shrager, J. B., Minugh-Purvis, N., Mitchell, M. A. Myosin gene mutation correlates with anatomical changes in the human lineage. Nature 428: 415-418, 2004.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005593-1	A15498	-	100 ug	$370		Add to Cart
BHA21005593-2	A15498-10ug	Sample	10 ug	$99		Add to Cart
BHA21005593-3	A15498-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005593-4	A15498-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005593-5	A15498-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005593-6	A15498-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005593-7	A15498-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005593-8	A15498-FITC	FITC	100 ug	$570		Add to Cart
BHA21005593-9	A15498-HRP	HRP	100 ug	$570		Add to Cart
BHA21005593-10	A15498-APC	APC	100 ug	$670		Add to Cart
BHA21005593-11	A15498-PE	PE	100 ug	$670		Add to Cart
BHA21005593-12	A15498-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005593-13	A15498-carrier-free	carrier-free	100 ug	$370		Add to Cart

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