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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MUC2 Antibody

SKU : BHA21001456

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Mfr.No.	A01212, A01212-10ug, A01212-Biotin, A01212-Cy3, A01212-Dylight488, A01212-Dylight550, A01212-Dylight594, A01212-FITC, A01212-HRP, A01212-APC, A01212-PE, A01212-iFluor647, A01212-carrier-free
Alternative Names	mucin 2, oligomeric mucus/gel-forming
Background	Mucin 2, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the mucin protein family. It is mapped to 11p15.5. Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80% by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium. The primary function of the MUC2 gene product is to provide a protective barrier between the epithelial surfaces and the gut lumen. There is decreased expression of MUC2 in colonic cancer and defective polymerization of secreted mucin in ulcerative colitis.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio <a href="https://www.bosterbio.com/anti-muc2-antibody-a01212-boster.html" style="color:#EA8D28;">Anti-MUC2</a> Antibody Picoband® catalog # A01212. Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rat.
Function	Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer muc
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human MUC2, which shares 86.1% amino acid (aa) sequence identity with both mouse and rat MUC2.
Isotype	Rabbit IgG
Molecular Weight	38 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Mucin-2; MUC-2; Intestinal mucin-2; MUC2; SMUC
Tissue Specificity	Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q02817
Gene Id	4583
Gene Name	MUC2
Subcellular Location	Secreted. In the intestine, secreted into the inner and outer mucus layers.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC
Description	Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat<br> Immunofluorescence, 5ug/ml, Human, Mouse<br>

Reference	1. Allen, A., Hutton, D. A., Pearson, J. P. The MUC2 gene product: a human intestinal mucin. Int. J. Biochem. Cell Biol. 30: 797-801, 1998.<br /><br />2. Rousseau K, Bye C, Kim YS, Gum JR, Swallow DM, Toribara NW (May 2004). "The complete genomic organization of the human MUC6 and MUC2 mucin genes". Genomics 83 (5): 9369.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001456-1	A01212	100 ug	-	$370		Add to Cart
BHA21001456-2	A01212-10ug	10 ug	Sample	$99		Add to Cart
BHA21001456-3	A01212-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001456-4	A01212-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001456-5	A01212-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001456-6	A01212-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001456-7	A01212-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001456-8	A01212-FITC	100 ug	FITC	$570		Add to Cart
BHA21001456-9	A01212-HRP	100 ug	HRP	$570		Add to Cart
BHA21001456-10	A01212-APC	100 ug	APC	$670		Add to Cart
BHA21001456-11	A01212-PE	100 ug	PE	$670		Add to Cart
BHA21001456-12	A01212-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001456-13	A01212-carrier-free	100 ug	carrier-free	$370		Add to Cart

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