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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MSF/SEPTIN9 Antibody Picoband®

SKU : BHA21004413

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Mfr.No.	A05279-3, A05279-3-10ug, A05279-3-Biotin, A05279-3-Cy3, A05279-3-Dylight488, A05279-3-Dylight550, A05279-3-Dylight594, A05279-3-FITC, A05279-3-HRP, A05279-3-APC, A05279-3-PE, A05279-3-iFluor647, A05279-3-carrier-free
Alternative Names	aldo-keto reductase family 1 member D1
Background	This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alteatively spliced transcript variants encoding different isoforms have been described.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MSF/SEPTIN9 Antibody Picoband® catalog # A05279-3. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta4-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthes
Host	Rabbit
Immunogen Region	E.coli-derived human MSF/SEPTIN9 recombinant protein (Position: R15-D282).
Isotype	Rabbit IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Aldo-keto reductase family 1 member D1; 3-oxo-5-beta-steroid 4-dehydrogenase; Delta (4)-3-ketosteroid 5-beta-reductase; Delta (4)-3-oxosteroid 5-beta-reductase; AKR1D1; SRD5B1
Tissue Specificity	Highly expressed in liver. Expressed in testis and weakly in colon.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9UHD8
Gene Id	10801
Gene Name	SEPTIN9
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	ELISA, IF, IHC, WB, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Mouse<br> Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry(Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Collie, A. M. B., Landsverk, M. L., Ruzzo, E., Mefford, H. C., Buysse, K., Adkins, J. R., Knutzen, D. M., Baett, K., Brown, R. H., Jr., Parry, G. J., Yum, S. W., Simpson, D. A., Olney, R. K., Chinnery, P. F., Eichler, E. E., Chance, P. F., Hannibal, M. C. Non-recurrent SEPT9 duplications cause hereditary neuralgic amyotrophy. J. Med. Genet. 47: 601-607, 2010.<br /><br />2. Hannibal, M. C., Ruzzo, E. K., Miller, L. R., Betz, B., Buchan, J. G., Knutzen, D. M., Baett, K., Landsverk, M. L., Brice, A., LeGue, E., Bedford, H. M., Worrall, B. B., Lovitt, S., Appel, S. H., Andermann, E., Bird, T. D., Chance, P. F. SEPT9 gene sequencing analysis reveals recurrent mutations in hereditary neuralgic amyotrophy. Neurology 72: 1755-1759, 2009. <br /><br />3. Kalikin, L. M., Sims, H. L., Petty, E. M. Genomic and expression analyses of alteatively spliced transcripts of the MLL septin-like fusion gene (MSF) that map to a 17q25 region of loss in breast and ovarian tumors. Genomics 63: 165-172, 2000.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004413-1	A05279-3	-	100 ug	$370		Add to Cart
BHA21004413-2	A05279-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21004413-3	A05279-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004413-4	A05279-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004413-5	A05279-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004413-6	A05279-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004413-7	A05279-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004413-8	A05279-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21004413-9	A05279-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21004413-10	A05279-3-APC	APC	100 ug	$670		Add to Cart
BHA21004413-11	A05279-3-PE	PE	100 ug	$670		Add to Cart
BHA21004413-12	A05279-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004413-13	A05279-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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