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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Morg1/WDR83 Antibody Picoband®

SKU : BHA21006639

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Mfr.No.	PA1053, PA1053-10ug, PA1053-Biotin, PA1053-Cy3, PA1053-Dylight488, PA1053-Dylight550, PA1053-Dylight594, PA1053-FITC, PA1053-HRP, PA1053-APC, PA1053-PE, PA1053-iFluor647, PA1053-carrier-free
Alternative Names	WD repeat domain-containing protein 83
Background	MORG1 (mitogen-activated protein kinase organizer 1), a member of the WD-40 protein family that was isolated as a binding partner of the extracellular signal-regulated kinase (ERK) pathway scaffold protein MP1. MORG1 specifically associates with several components of the ERK pathway, including MP1, Raf-1, MEK, and ERK, and stabilizes their assembly into an oligomeric complex. MORG1 facilitates ERK activation when cells are stimulated with lysophosphatidic acid, phorbol 12-myristate 13-acetate, or serum, but not in response to epidermal growth factor. Suppression of MORG1 by short interfering RNA leads to a marked reduction in ERK activity when cells are stimulated with serum. MORG1 is a component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Morg1/WDR83 Antibody catalog # PA1053. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas h
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human Morg1, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	12 kDa
Reactivity	Rat, Mouse, Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	WD repeat domain-containing protein 83;Mitogen-activated protein kinase organizer 1;MAPK organizer 1;WDR83;MORG1;
Tissue Specificity	MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q9BRX9
Gene Name	WDR83
Sequence	Belongs to the WD repeat MORG1 family.
Subcellular Location	Cytoplasm . Nucleus . Predominantly cytoplasmic. Partially nuclear. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1. Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists. Vomastek T, Schaeffer HJ, Tarcsafalvi A, Smolkin ME, Bissonette EA, Weber MJ. Department of Microbiology and Cancer Center, University of Virginia, Charlottesville, VA 22908, USA.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006639-1	PA1053	-	100 ug	$370		Add to Cart
BHA21006639-2	PA1053-10ug	Sample	10 ug	$99		Add to Cart
BHA21006639-3	PA1053-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006639-4	PA1053-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006639-5	PA1053-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006639-6	PA1053-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006639-7	PA1053-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006639-8	PA1053-FITC	FITC	100 ug	$570		Add to Cart
BHA21006639-9	PA1053-HRP	HRP	100 ug	$570		Add to Cart
BHA21006639-10	PA1053-APC	APC	100 ug	$670		Add to Cart
BHA21006639-11	PA1053-PE	PE	100 ug	$670		Add to Cart
BHA21006639-12	PA1053-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006639-13	PA1053-carrier-free	carrier-free	100 ug	$370		Add to Cart

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