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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Monoamine Oxidase B/MAOB Antibody Picoband®

SKU : BHA21006956

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Mfr.No.	PA1649, PA1649-10ug, PA1649-Biotin, PA1649-Cy3, PA1649-Dylight488, PA1649-Dylight550, PA1649-Dylight594, PA1649-FITC, PA1649-HRP, PA1649-APC, PA1649-PE, PA1649-iFluor647, PA1649-carrier-free
Alternative Names	Amine oxidase (flavin-containing) B
Background	MAOB (MONOAMINE OXIDASE B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Monoamine Oxidase B/MAOB Antibody catalog # PA1649. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phe
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of mouse MAOB, identical to the related rat sequence.
Isotype	Rabbit IgG
Molecular Weight	59 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Amine oxidase (flavin-containing) B;1.4.3.4;Monoamine oxidase type B;MAO-B;Maob;
Tissue Specificity	Heart, liver, duodenum, blood vessels and kidney.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q8BW75
Gene Name	MAOB
Sequence	Belongs to the flavin monoamine oxidase family.
Subcellular Location	Mitochondrion outer membrane ; Single-pass type IV membrane protein ; Cytoplasmic side .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, Rat, By Heat <br>Weste blot, 0.1-0.5ug/ml, Mouse, Rat<br>

Reference	1. Bach, A. W., Lan, N. C., Johnson, D. L., Abell, C. W., Bembenek, M. E., Kwan, S.-W., Seeburg, P. H., Shih, J. C. cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc. Nat. Acad. Sci. 85: 4934-4938, 1988.<br /><br />2. Binda, C., Newton-Vinson, P., Hubalek, F., Edmondson, D. E., Mattevi, A. Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders. Nature Struct. Biol. 9: 22-26, 2002.<br /><br />3. Edmondson DE, Binda C, Mattevi A (2007). "STRUCTURAL INSIGHTS INTO THE MECHANISM OF AMINE OXIDATION BY MONOAMINE OXIDASES A AND B". Archives of Biochemistry and Biophysics 464 (2): 26976.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006956-1	PA1649	-	100 ug	$370		Add to Cart
BHA21006956-2	PA1649-10ug	Sample	10 ug	$99		Add to Cart
BHA21006956-3	PA1649-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006956-4	PA1649-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006956-5	PA1649-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006956-6	PA1649-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006956-7	PA1649-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006956-8	PA1649-FITC	FITC	100 ug	$570		Add to Cart
BHA21006956-9	PA1649-HRP	HRP	100 ug	$570		Add to Cart
BHA21006956-10	PA1649-APC	APC	100 ug	$670		Add to Cart
BHA21006956-11	PA1649-PE	PE	100 ug	$670		Add to Cart
BHA21006956-12	PA1649-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006956-13	PA1649-carrier-free	carrier-free	100 ug	$370		Add to Cart

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