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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MMP16 Antibody Picoband®

SKU : BHA21001353

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Mfr.No.	A05065, A05065-10ug, A05065-Biotin, A05065-Cy3, A05065-Dylight488, A05065-Dylight550, A05065-Dylight594, A05065-FITC, A05065-HRP, A05065-APC, A05065-PE, A05065-iFluor647, A05065-carrier-free
Alternative Names	matrix metallopeptidase 16
Background	The matrix metalloproteinase 16 (MMP16) protein consists of 604 amino acids and has a characteristic MMP domain structure, which gene is mapped on human chromosome 8q21. Additionally, MMP16 has a C-terminal extension containing a potential transmembrane domain, similar to MMP14, MMP15, and MMP17. Furthermore, it is membrane-bound and is a member of the membrane-type MMPs that are a subclass in the MMP family since the other members lack a C-terminal transmembrane domain and are secreted as soluble forms. MMP16 is expressed as a 12-kb transcript in brain, placenta, heart, and some carcinoma cell lines, but is not detectably expressed in lung, kidney, liver, spleen, and muscle.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MMP16 Antibody Picoband® catalog # A05065. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type
Host	Rabbit
Immunogen Region	E. coli-derived human MMP16 recombinant protein (Position: Y120-I296).
Isotype	Rabbit IgG
Molecular Weight	53 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Matrix metalloproteinase-16; MMP-16; 3.4.24.-; MMP-X2; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3-MMP; MT3MMP; MMP16; MMPX2;
Tissue Specificity	Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	MMP16: P51512
Gene Id	4325
Gene Name	MMP16
Subcellular Location	Isoform Long: Cell membrane ; Localized at the cell surface of melanoma cells.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunocytochemistry/Immunofluorescence, 2ug/ml<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Sato, H.; Tanaka, M.; Takino, T.; Inoue, M.; Seiki, M. : Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization. Genomics 39: 412-413, 1997.<br /><br />2. Takino, T.; Sato, H.; Shinagawa, A.; Seiki, M. : Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library: MT-MMPs form a unique membrane-type subclass in the MMP family. J. Biol. Chem. 270: 23013-23020, 1995.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001353-1	A05065	100 ug	-	$370		Add to Cart
BHA21001353-2	A05065-10ug	10 ug	Sample	$99		Add to Cart
BHA21001353-3	A05065-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001353-4	A05065-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001353-5	A05065-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001353-6	A05065-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001353-7	A05065-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001353-8	A05065-FITC	100 ug	FITC	$570		Add to Cart
BHA21001353-9	A05065-HRP	100 ug	HRP	$570		Add to Cart
BHA21001353-10	A05065-APC	100 ug	APC	$670		Add to Cart
BHA21001353-11	A05065-PE	100 ug	PE	$670		Add to Cart
BHA21001353-12	A05065-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001353-13	A05065-carrier-free	100 ug	carrier-free	$370		Add to Cart

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