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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MMP1 Antibody Picoband®

SKU : BHA21000625

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Mfr.No.	PB9725, PB9725-10ug, PB9725-Biotin, PB9725-Cy3, PB9725-Dylight488, PB9725-Dylight550, PB9725-Dylight594, PB9725-FITC, PB9725-HRP, PB9725-APC, PB9725-PE, PB9725-iFluor647, PB9725-carrier-free
Alternative Names	Interstitial collagenase
Background	Matrix metalloproteinase-1 (MMP-1), also known as interstitial collagenase and fibroblast collagenase, is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 was the first vertebrate collagenase both purified to homogeneity as a protein, and cloned as a cDNA. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. It is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MMP1 Antibody Picoband® catalog # PB9725. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurot
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human MMP1.
Isotype	Rabbit IgG
Molecular Weight	54 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interstitial collagenase;3.4.24.7;Fibroblast collagenase;Matrix metalloproteinase-1;MMP-1;22 kDa interstitial collagenase;27 kDa interstitial collagenase;MMP1;CLG;
Tissue Specificity	Colon, lymphocytes, breast, lung, spleen, testis, prostate, thyroid, gall bladder and heart.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P03956
Gene Id	4312
Gene Name	MMP1
Subcellular Location	Secreted, extracellular space, extracellular matrix .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human

Reference	1. Huang SF, Li YH, Ren YJ, Cao ZG, Long X (August 2008). "The effect of a single nucleotide polymorphism in the matrix metalloproteinase-1 (MMP-1) promoter on force-induced MMP-1 expression in human periodontal ligament cells". Eur. J. Oral Sci. 116 (4): 31923. 2. Pendás AM, Santamaría I, Alvarez MV, Pritchard M, López-Otín C (October 1996). "Fine physical mapping of the human matrix metalloproteinase genes clustered on chromosome 11q22.3". Genomics 37 (2): 2668.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000625-1	PB9725	100 ug	-	$370		Add to Cart
BHA21000625-2	PB9725-10ug	10 ug	Sample	$99		Add to Cart
BHA21000625-3	PB9725-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000625-4	PB9725-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000625-5	PB9725-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000625-6	PB9725-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000625-7	PB9725-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000625-8	PB9725-FITC	100 ug	FITC	$570		Add to Cart
BHA21000625-9	PB9725-HRP	100 ug	HRP	$570		Add to Cart
BHA21000625-10	PB9725-APC	100 ug	APC	$670		Add to Cart
BHA21000625-11	PB9725-PE	100 ug	PE	$670		Add to Cart
BHA21000625-12	PB9725-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000625-13	PB9725-carrier-free	100 ug	carrier-free	$370		Add to Cart

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