JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-MGMT Antibody Picoband®

SKU : BHA21000155

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PB9266, PB9266-10ug, PB9266-Biotin, PB9266-Cy3, PB9266-Dylight488, PB9266-Dylight550, PB9266-Dylight594, PB9266-FITC, PB9266-HRP, PB9266-APC, PB9266-PE, PB9266-iFluor647, PB9266-carrier-free
Alternative Names	Methylated-DNA--protein-cysteine methyltransferase
Background	O6-alkylguanine DNA alkyltransferase (also known as AGT, MGMT or AGAT) is a protein that in humans is encoded by the O6-methylguanine DNA methyltransferase (MGMT) gene. MGMT is mapped to 10q26.3. This gene is crucial for genome stability. It repairs the naturally occurring mutagenic DNA lesion O6-methylguanine back to guanine and prevents mismatch and errors during DNA replication and transcription. It has been found that methylation of the MGMT promoter in the tumor was associated with longer survival.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-MGMT Antibody Picoband® catalog # PB9266. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a sui
Host	Rabbit
Immunogen Region	E.coli-derived human MGMT recombinant protein (Position: D2-N207). Human MGMT shares 70% and 69% amino acid (aa) sequence identity with mouse and rat MGMT, respectively.
Isotype	Rabbit IgG
Molecular Weight	22 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Methylated-DNA--protein-cysteine methyltransferase;2.1.1.63;6-O-methylguanine-DNA methyltransferase;MGMT;O-6-methylguanine-DNA-alkyltransferase;MGMT;
Tissue Specificity	Ubiquitous; expressed at low level. Highly expressed in heart and kidney. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P16455
Gene Id	4255
Gene Name	MGMT
Sequence	Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, By Heat Immunocytochemistry , 0.5-1ug/ml, Human Immunocytochemistry/Immunofluorescence, 2ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. Hegi, M. E., Diserens, A.-C., Godard, S., Dietrich, P.-Y., Regli, L., Ostermann, S., Otten, P., Van Melle, G., de Tribolet, N., Stupp, R. Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin. Cancer Res. 10: 1871-1874, 2004. 2. Natarajan AT, Vermeulen S, Darroudi F, Valentine MB, Brent TP, Mitra S, Tano K (January 1992). "Chromosomal localization of human O6-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization". Mutagenesis 7 (1): 835. 3. Shiraishi A, Sakumi K, Sekiguchi M (October 2000). "Increased susceptibility to chemotherapeutic alkylating agents of mice deficient in DNA repair methyltransferase". Carcinogenesis 21 (10): 18791883.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000155-1	PB9266	100 ug	-	$370		Add to Cart
BHA21000155-2	PB9266-10ug	10 ug	Sample	$99		Add to Cart
BHA21000155-3	PB9266-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000155-4	PB9266-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000155-5	PB9266-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000155-6	PB9266-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000155-7	PB9266-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000155-8	PB9266-FITC	100 ug	FITC	$570		Add to Cart
BHA21000155-9	PB9266-HRP	100 ug	HRP	$570		Add to Cart
BHA21000155-10	PB9266-APC	100 ug	APC	$670		Add to Cart
BHA21000155-11	PB9266-PE	100 ug	PE	$670		Add to Cart
BHA21000155-12	PB9266-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000155-13	PB9266-carrier-free	100 ug	carrier-free	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.