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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Mesp2 Antibody Picoband®

SKU : BHA21002934

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Mfr.No.	A07046-1, A07046-1-10ug, A07046-1-Biotin, A07046-1-Cy3, A07046-1-Dylight488, A07046-1-Dylight550, A07046-1-Dylight594, A07046-1-FITC, A07046-1-HRP, A07046-1-APC, A07046-1-PE, A07046-1-iFluor647, A07046-1-carrier-free
Alternative Names	forkhead box K1
Background	Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene. This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patteing of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Mesp2 Antibody Picoband® catalog # A07046-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis, muscle cell differentiation and autophagy. Recognizes and binds the forkhead DNA sequence motif (5'-GTAAACA-3') and can both act as a transcription a
Host	Rabbit
Immunogen Region	E.coli-derived human Mesp2 recombinant protein (Position: M1-Y397).
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Forkhead box protein F1; Forkhead-related activator 1; FREAC-1; Forkhead-related protein FKHL5; Forkhead-related transcription factor 1; FOXF1; FKHL5; FREAC1
Tissue Specificity	Expressed in kidney.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	Q0VG99
Gene Id	145873
Gene Name	MESP2
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Coier, A. S., Staehling-Hampton, K., Delventhal, K. M., Saga, Y., Caubet, J.-F., Sasaki, N., Ellard, S., Young, E., Ramirez, N., Carlo, S. E., Torres, J., Emans, J. B., Tupenny, P. D., Pourquie, O. Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome. Am. J. Hum. Genet. 82: 1334-1341, 2008. <br /><br />2. Morimoto, M., Takahashi, Y., Endo, M., Saga, Y. The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature 435: 354-359, 2005. <br /><br />3. Saga, Y., Hata, N., Koseki, H., Taketo, M. M. Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 11: 1827-1839, 1997.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002934-1	A07046-1	-	100 ug	$370		Add to Cart
BHA21002934-2	A07046-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21002934-3	A07046-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002934-4	A07046-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002934-5	A07046-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002934-6	A07046-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002934-7	A07046-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002934-8	A07046-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21002934-9	A07046-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21002934-10	A07046-1-APC	APC	100 ug	$670		Add to Cart
BHA21002934-11	A07046-1-PE	PE	100 ug	$670		Add to Cart
BHA21002934-12	A07046-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002934-13	A07046-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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