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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Mesothelin/MSLN Antibody

SKU : BHA21000570

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Mfr.No.	PB9671, PB9671-10ug, PB9671-Biotin, PB9671-Cy3, PB9671-Dylight488, PB9671-Dylight550, PB9671-Dylight594, PB9671-FITC, PB9671-HRP, PB9671-APC, PB9671-PE, PB9671-iFluor647, PB9671-carrier-free
Alternative Names	Mesothelin
Background	Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Mesothelin/MSLN Antibody Picoband® catalog # PB9671. Tested in IHC applications. This antibody reacts with Mouse.
Function	Membrane-anchored forms may play a role in cellular adhesion. .
Host	Rabbit
Immunogen Region	E.coli-derived mouse Mesothelin recombinant protein (Position: K308-L576). Mouse Mesothelin shares 58.4%% and 89.6% amino acid (aa) sequence identity with human and rat Mesothelin, respectively.
Isotype	Rabbit IgG
Molecular Weight	54 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Mesothelin;Pre-pro-megakaryocyte-potentiating factor;Megakaryocyte-potentiating factor;MPF;Mesothelin, cleaved form;Msln;Mes, Mpf;
Tissue Specificity	Highly expressed in lung and heart. Expressed at low levels in spleen, liver, kidney and testis. Present in lung (at protein level). .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q61468
Gene Id	56047
Gene Name	Msln
Subcellular Location	Cell membrane ; Lipid-anchor, GPI-anchor . Golgi apparatus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, By Heat

Reference	1. Bera, T. K., Pastan, I. Mesothelin is not required for normal mouse development or reproduction. Molec. Cell. Biol. 20: 2902-2906, 2000. 2. Scholler, N., Fu, N., Yang, Y., Ye, Z., Goodman, G. E., Hellstrom, K. E., Hellstrom, I. Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma. Proc. Nat. Acad. Sci. 96: 11531-11536, 1999.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000570-1	PB9671	100 ug	-	$370		Add to Cart
BHA21000570-2	PB9671-10ug	10 ug	Sample	$99		Add to Cart
BHA21000570-3	PB9671-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000570-4	PB9671-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000570-5	PB9671-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000570-6	PB9671-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000570-7	PB9671-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000570-8	PB9671-FITC	100 ug	FITC	$570		Add to Cart
BHA21000570-9	PB9671-HRP	100 ug	HRP	$570		Add to Cart
BHA21000570-10	PB9671-APC	100 ug	APC	$670		Add to Cart
BHA21000570-11	PB9671-PE	100 ug	PE	$670		Add to Cart
BHA21000570-12	PB9671-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000570-13	PB9671-carrier-free	100 ug	carrier-free	$370		Add to Cart

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