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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Mesothelin/Msln Antibody Picoband®

SKU : BHA21005607

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Mfr.No.	A03266-1, A03266-1-10ug, A03266-1-Biotin, A03266-1-Cy3, A03266-1-Dylight488, A03266-1-Dylight550, A03266-1-Dylight594, A03266-1-FITC, A03266-1-HRP, A03266-1-APC, A03266-1-PE, A03266-1-iFluor647, A03266-1-carrier-free
Alternative Names	leucine rich pentatricopeptide repeat containing
Background	Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Mesothelin/Msln Antibody Picoband® catalog # A03266-1. Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly (A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind m
Host	Rabbit
Immunogen Region	E.coli-derived mouse Mesothelin/Msln recombinant protein (Position: Q44-K497).
Isotype	Rabbit IgG
Molecular Weight	69 kDa
Reactivity	Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Leucine-rich PPR motif-containing protein, mitochondrial; 130 kDa leucine-rich protein; LRP 130; GP130; LRPPRC; LRP130
Tissue Specificity	Expressed ubiquitously. Expression is highest in heart, skeletal muscle, kidney and liver, intermediate in brain, non-mucosal colon, spleen and placenta, and lowest in small intestine, thymus, lung and peripheral blood leukocytes.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q61468
Gene Id	56047
Gene Name	Msln
Subcellular Location	Mitochondrion. Nucleoplasm. Nucleus inner membrane. Nucleus outer membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Mouse<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Bera, T. K., Pastan, I. Mesothelin is not required for normal mouse development or reproduction. Molec. Cell. Biol. 20: 2902-2906, 2000. <br /><br />2. Scholler, N., Fu, N., Yang, Y., Ye, Z., Goodman, G. E., Hellstrom, K. E., Hellstrom, I. Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma. Proc. Nat. Acad. Sci. 96: 11531-11536, 1999.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005607-1	A03266-1	-	100 ug	$370		Add to Cart
BHA21005607-2	A03266-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21005607-3	A03266-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005607-4	A03266-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005607-5	A03266-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005607-6	A03266-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005607-7	A03266-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005607-8	A03266-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21005607-9	A03266-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21005607-10	A03266-1-APC	APC	100 ug	$670		Add to Cart
BHA21005607-11	A03266-1-PE	PE	100 ug	$670		Add to Cart
BHA21005607-12	A03266-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005607-13	A03266-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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