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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MEK2/MAP2K2 Antibody Picoband®

SKU : BHA21007439

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Mfr.No.	PA2274, PA2274-10ug, PA2274-Biotin, PA2274-Cy3, PA2274-Dylight488, PA2274-Dylight550, PA2274-Dylight594, PA2274-FITC, PA2274-HRP, PA2274-APC, PA2274-PE, PA2274-iFluor647, PA2274-carrier-free
Alternative Names	Dual specificity mitogen-activated protein kinase kinase 2
Background	Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2), also called PRKMK2 or MEK2, is an enzyme that in humans is encoded by the MAP2K2 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. MAP2K2 is mapped to 19p13.3. This kinase is known to play a critical role in mitogen growth factor signal transduction, and the inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax. Recombinant MEK2 and MEK1 both could activate human ERK1 in vitro, and they further characterized biochemically the 2 MAP2Ks. MAP2K2 has been shown to interact with MAPK3 and ARAF.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-MEK2/MAP2K2 Antibody catalog # PA2274. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human MEK2, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Dual specificity mitogen-activated protein kinase kinase 2;MAP kinase kinase 2;MAPKK 2;2.7.12.2;ERK activator kinase 2;MAPK/ERK kinase 2;MEK 2;MAP2K2;MEK2, MKK2, PRKMK2;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P36507
Gene Name	MAP2K2
Sequence	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1.Entrez Gene: MAP2K2 mitogen-activated protein kinase kinase 2"<br /><br />2. Zheng, C. F., Guan, K. L. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2. J. Biol. Chem. 268: 11435-11439, 1993.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007439-1	PA2274	-	100 ug	$370		Add to Cart
BHA21007439-2	PA2274-10ug	Sample	10 ug	$99		Add to Cart
BHA21007439-3	PA2274-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007439-4	PA2274-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007439-5	PA2274-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007439-6	PA2274-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007439-7	PA2274-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007439-8	PA2274-FITC	FITC	100 ug	$570		Add to Cart
BHA21007439-9	PA2274-HRP	HRP	100 ug	$570		Add to Cart
BHA21007439-10	PA2274-APC	APC	100 ug	$670		Add to Cart
BHA21007439-11	PA2274-PE	PE	100 ug	$670		Add to Cart
BHA21007439-12	PA2274-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007439-13	PA2274-carrier-free	carrier-free	100 ug	$370		Add to Cart

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