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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MEK2/MAP2K2 Antibody Picoband®

SKU : BHA21003703

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Mfr.No.	A00996-3, A00996-3-10ug, A00996-3-Biotin, A00996-3-Cy3, A00996-3-Dylight488, A00996-3-Dylight550, A00996-3-Dylight594, A00996-3-FITC, A00996-3-HRP, A00996-3-APC, A00996-3-PE, A00996-3-iFluor647, A00996-3-carrier-free
Alternative Names	protein kinase AMP-activated catalytic subunit alpha 1
Background	Dual specificity mitogen-activated protein kinase kinase 2(MAP2K2), also called PRKMK2 or MEK2, is an enzyme that in humans is encoded by the MAP2K2 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. MAP2K2 is mapped to 19p13.3. This kinase is known to play a critical role in mitogen growth factor signal transduction, and the inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax. Recombinant MEK2 and MEK1 both could activate human ERK1 in vitro, and they further characterized biochemically the 2 MAP2Ks. MAP2K2 has been shown to interact with MAPK3 and ARAF.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MEK2/MAP2K2 Antibody Picoband® catalog # A00996-3. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and in
Host	Rabbit
Immunogen Region	E.coli-derived human MEK2/MAP2K2 recombinant protein (Position: M1-E45).
Isotype	Rabbit IgG
Molecular Weight	44 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1
Tissue Specificity	Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P36507
Gene Id	5605
Gene Name	MAP2K2
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	ELISA, Flow Cytometry, WB
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Rat ELISA, 0.1-0.5 ug/ml, -

Reference	1.Entrez Gene: MAP2K2 mitogen-activated protein kinase kinase 2" 2. Zheng, C. F., Guan, K. L. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2. J. Biol. Chem. 268: 11435-11439, 1993.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003703-1	A00996-3	-	100 ug	$370		Add to Cart
BHA21003703-2	A00996-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21003703-3	A00996-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003703-4	A00996-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003703-5	A00996-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003703-6	A00996-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003703-7	A00996-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003703-8	A00996-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21003703-9	A00996-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21003703-10	A00996-3-APC	APC	100 ug	$670		Add to Cart
BHA21003703-11	A00996-3-PE	PE	100 ug	$670		Add to Cart
BHA21003703-12	A00996-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003703-13	A00996-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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