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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MCSF/CSF1 Antibody

SKU : BHA21000458

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Mfr.No.	PB9562, PB9562-10ug, PB9562-Biotin, PB9562-Cy3, PB9562-Dylight488, PB9562-Dylight550, PB9562-Dylight594, PB9562-FITC, PB9562-HRP, PB9562-APC, PB9562-PE, PB9562-iFluor647, PB9562-carrier-free
Alternative Names	Macrophage colony-stimulating factor 1
Background	M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-MCSF/CSF1 Antibody Picoband® catalog # PB9562. Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.
Function	Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokin
Host	Rabbit
Immunogen Region	E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.
Isotype	Rabbit IgG
Molecular Weight	130 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Macrophage colony-stimulating factor 1;CSF-1;MCSF;Processed macrophage colony-stimulating factor 1;Csf1;Csfm;
Tissue Specificity	Non-neural epithelial tissues.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P07141
Gene Id	12977
Gene Name	Csf1
Sequence	Contains 5 cadherin domains.
Subcellular Location	Cell membrane ; Single-pass type I membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC
Description	ELISA, 0.1-0.5ug/ml, - Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, Rat, By Heat

Reference	1. Fixe P, Praloran V (June 1997)."Macrophage colony-stimulating-factor (M-CSF or CSF-1) and its receptor: structure-function relationships". Eur. Cytokine Netw. 8 (2): 12536. 2. Nemunaitis J (April 1993). "Macrophage function activating cytokines: potential clinical application". Crit. Rev. Oncol. Hematol. 14 (2): 15371. 3. Stanley ER, Berg KL, Einstein DB, Lee PS, Pixley FJ, Wang Y, Yeung YG (January 1997). "Biology and action of colony--stimulating factor-1". Mol. Reprod. Dev. 46(1): 410.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000458-1	PB9562	100 ug	-	$370		Add to Cart
BHA21000458-2	PB9562-10ug	10 ug	Sample	$99		Add to Cart
BHA21000458-3	PB9562-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000458-4	PB9562-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000458-5	PB9562-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000458-6	PB9562-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000458-7	PB9562-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000458-8	PB9562-FITC	100 ug	FITC	$570		Add to Cart
BHA21000458-9	PB9562-HRP	100 ug	HRP	$570		Add to Cart
BHA21000458-10	PB9562-APC	100 ug	APC	$670		Add to Cart
BHA21000458-11	PB9562-PE	100 ug	PE	$670		Add to Cart
BHA21000458-12	PB9562-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000458-13	PB9562-carrier-free	100 ug	carrier-free	$370		Add to Cart

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