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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MCP4/CCL13 Antibody Picoband®

SKU : BHA21007492

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Mfr.No.	PB9030, PB9030-10ug, PB9030-Biotin, PB9030-Cy3, PB9030-Dylight488, PB9030-Dylight550, PB9030-Dylight594, PB9030-FITC, PB9030-HRP, PB9030-APC, PB9030-PE, PB9030-iFluor647, PB9030-carrier-free
Alternative Names	C-C motif chemokine 13
Background	Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family. Its gene is located on human chromosome 17 within a large cluster of other CC chemokines. CCL13 induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. Activity of this chemokine has been implicated in allergic reactions such as asthma. CCL13 can be induced by the inflammatory cytokines interleukin-1 and TNF-alpha.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-MCP4/CCL13 Antibody Picoband® catalog # PB9030. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May
Host	Rabbit
Immunogen Region	E.coli-derived human MCP4 recombinant protein (Position: Q24-T98).
Isotype	Rabbit IgG
Molecular Weight	34 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	C-C motif chemokine 13;CK-beta-10;Monocyte chemoattractant protein 4;Monocyte chemotactic protein 4;MCP-4;NCC-1;Small-inducible cytokine A13;C-C motif chemokine 13, long chain;C-C motif chemokine 13, medium chain;C-C motif chemokine 13, short chain;CCL13;MCP4, NCC1, SCYA13;
Tissue Specificity	Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q99616
Gene Id	6357
Gene Name	CCL13
Sequence	Belongs to the intercrine beta (chemokine CC) family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, -<br>ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Garcia-Zepeda EA, et al.. Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and no allergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3. J Immunol. 1996;157:56135626<br /><br />2. Naruse et al., A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. Genomics. 1996, 34(2):236-40.<br /><br />3. Blanpain et al., CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood. 1999, 94:1899-905.<br /><br />4. Lamkhioued et al., Monocyte chemoattractant protein (MCP)-4 expression in the airways of patients with asthma. Induction in epithelial cells and mononuclear cells by proinflammatory cytokines. Am J Respir Crit Care Med. 2000, 162:723-32.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007492-1	PB9030	-	100 ug	$370		Add to Cart
BHA21007492-2	PB9030-10ug	Sample	10 ug	$99		Add to Cart
BHA21007492-3	PB9030-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007492-4	PB9030-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007492-5	PB9030-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007492-6	PB9030-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007492-7	PB9030-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007492-8	PB9030-FITC	FITC	100 ug	$570		Add to Cart
BHA21007492-9	PB9030-HRP	HRP	100 ug	$570		Add to Cart
BHA21007492-10	PB9030-APC	APC	100 ug	$670		Add to Cart
BHA21007492-11	PB9030-PE	PE	100 ug	$670		Add to Cart
BHA21007492-12	PB9030-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007492-13	PB9030-carrier-free	carrier-free	100 ug	$370		Add to Cart

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