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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MAD2L2 Antibody Picoband®

SKU : BHA21005528

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Mfr.No.	A02357-4, A02357-4-10ug, A02357-4-Biotin, A02357-4-Cy3, A02357-4-Dylight488, A02357-4-Dylight550, A02357-4-Dylight594, A02357-4-FITC, A02357-4-HRP, A02357-4-APC, A02357-4-PE, A02357-4-iFluor647, A02357-4-carrier-free
Alternative Names	calcitonin/calcitonin-related polypeptide, alpha
Background	Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene. The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MAD2L2 Antibody Picoband® catalog # A02357-4. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Host	Rabbit
Immunogen Region	E.coli-derived human MAD2L2 recombinant protein (Position: M1-K209).
Isotype	Rabbit IgG
Molecular Weight	24 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Calcitonin; Calca; Calc
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9UI95
Gene Id	10459
Gene Name	MAD2L2
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	ELISA, IF, IHC, ICC, WB, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Bluteau, D., Masliah-Planchon, J., Clairmont, C., Rousseau, A., Ceccaldi, R., Dubois d'Enghien, C., Bluteau, O., Cuccuini, W., Gachet, S., Peffault de Latour, R., Leblanc, T., Socie, G., Baruchel, A., Stoppa-Lyonnet, D., D'Andrea, A. D., Soulier, J. Biallelic inactivation of REV7 is associated with Fanconi anemia. J. Clin. Invest. 126: 3580-3584, 2016. Note: Erratum: J. Clin. Invest. 127: 1117 only, 2017.<br /><br />2. Boersma, V., Moatti, N., Segura-Bayona, S., Peuscher, M. H., van der Torre, J., Wevers, B. A., Orthwein, A., Durocher, D., Jacobs, J. J. L. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5-prime end resection. Nature 521: 537-540, 2015. <br /><br />3. Cahill, D. P., da Costa, L. T., Carson-Walter, E. B., Kinzler, K. W., Vogelstein, B., Lengauer, C. Characterization of MAD2B and other mitotic spindle checkpoint genes. Genomics 58: 181-187, 1999.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005528-1	A02357-4	-	100 ug	$370		Add to Cart
BHA21005528-2	A02357-4-10ug	Sample	10 ug	$99		Add to Cart
BHA21005528-3	A02357-4-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005528-4	A02357-4-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005528-5	A02357-4-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005528-6	A02357-4-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005528-7	A02357-4-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005528-8	A02357-4-FITC	FITC	100 ug	$570		Add to Cart
BHA21005528-9	A02357-4-HRP	HRP	100 ug	$570		Add to Cart
BHA21005528-10	A02357-4-APC	APC	100 ug	$670		Add to Cart
BHA21005528-11	A02357-4-PE	PE	100 ug	$670		Add to Cart
BHA21005528-12	A02357-4-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005528-13	A02357-4-carrier-free	carrier-free	100 ug	$370		Add to Cart

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