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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Macrophage Inflammatory Protein 4/CCL18 Antibody Picoband®

SKU : BHA21007485

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Mfr.No.	PB9023, PB9023-10ug, PB9023-Biotin, PB9023-Cy3, PB9023-Dylight488, PB9023-Dylight550, PB9023-Dylight594, PB9023-FITC, PB9023-HRP, PB9023-APC, PB9023-PE, PB9023-iFluor647, PB9023-carrier-free
Alternative Names	C-C motif chemokine 18
Background	Macrophage Inflammatory Protein 4, also known as CCL18, is a small cytokine belonging to the CC chemokine family that was previously called PARC (pulmonary and activation-regulated chemokine). CCL18 is approximately 60% identical in amino acid sequence to CCL3. By analysis of a previously mapped CCL18 from 17q11.2, it is determined that the PARC gene is located within 1 of the 2 clusters of CC chemokine genes in this region. It is expressed at high levels in lung and at lower levels in certain lymphoid tissues, such as the lymph nodes, and is chemotactic for activated T cells and nonactivated lymphocytes. Beside, CCL18 recruits Th2 cells and basophils and may play a predominant role in allergic asthma.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Macrophage Inflammatory Protein 4/CCL18 Antibody Picoband® catalog # PB9023. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has che
Host	Rabbit
Immunogen Region	E.coli-derived human CCL18 recombinant protein (Position: A21-A89).
Isotype	Rabbit IgG
Molecular Weight	19 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	C-C motif chemokine 18;Alteative macrophage activation-associated CC chemokine 1;AMAC-1;CC chemokine PARC;Dendritic cell chemokine 1;DC-CK1;Macrophage inflammatory protein 4;MIP-4;Pulmonary and activation-regulated chemokine;Small-inducible cytokine A18;CCL18 (1-68);CCL18 (3-69);CCL18 (4-69);CCL18;AMAC1, DCCK1, MIP4, PARC, SCYA18;
Tissue Specificity	Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P55774
Gene Id	6362
Gene Name	CCL18
Sequence	Belongs to the intercrine beta (chemokine CC) family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, -<br> ELISA(Cap) , 1-5ug/ml, Human<br>

Reference	1. Hieshima k, I. T. (August 1997). "A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes". Joual of Immunology 159 (3): 11401149.<br /><br />2. Tasaki, Y.; Fukuda, S.; Iio, M.; Miura, R.; Imai, T.; Sugano, S.; Yoshie, O.; Hughes, A. et al. (1999). "Chemokine PARC Gene (SCYA18) Generated by Fusion of Two MIP-1alpha/LD78alpha-like Genes, ,". Genomics 55 (3): 353357. <br /><br />3. Hieshima, K., Imai, T., Baba, M., Shoudai, K., Ishizuka, K., Nakagawa, T., Tsuruta, J., Takeya, M., Sakaki, Y., Takatsuki, K., Miura, R., Opdenakker, G., Van Damme, J., Yoshie, O., Nomiyama, H. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1-alpha/LD78-alpha and chemotactic for T lymphocytes, but not for monocytes. J. Immun. 159: 1140-1149, 1997.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007485-1	PB9023	-	100 ug	$370		Add to Cart
BHA21007485-2	PB9023-10ug	Sample	10 ug	$99		Add to Cart
BHA21007485-3	PB9023-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007485-4	PB9023-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007485-5	PB9023-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007485-6	PB9023-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007485-7	PB9023-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007485-8	PB9023-FITC	FITC	100 ug	$570		Add to Cart
BHA21007485-9	PB9023-HRP	HRP	100 ug	$570		Add to Cart
BHA21007485-10	PB9023-APC	APC	100 ug	$670		Add to Cart
BHA21007485-11	PB9023-PE	PE	100 ug	$670		Add to Cart
BHA21007485-12	PB9023-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007485-13	PB9023-carrier-free	carrier-free	100 ug	$370		Add to Cart

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