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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Lyz1/2 Antibody Picoband®

SKU : BHA21006186

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Mfr.No.	A32724, A32724-10ug, A32724-Biotin, A32724-Cy3, A32724-Dylight488, A32724-Dylight550, A32724-Dylight594, A32724-FITC, A32724-HRP, A32724-APC, A32724-PE, A32724-iFluor647, A32724-carrier-free
Background	Lysozymes are secreted proteins that have bacteriolytic function which are critical for mammalian innate immune function. All lysozymes function to defend host animals from microbial infection by the hydrolysis of bacterial cell wall peptidoglycan. Conventional-type lysozymes (Lysozyme C) are one of three types of lysozymes; each family member is categorized based on amino acid sequence and biochemical properties. Lysozyme C is expressed in mammalian secretions like tears, urine, and milk but is also expressed by phagocytes such as macrophages, neutrophils, and dendritic cells. Lysozyme C is encoded in humans by a single LYZ gene. The mouse orthologs of Lysozyme C are encoded by two genes, Lyz1 and Lyz2, which encode Lysozyme C-1 and Lysozyme C-2 (Lysozyme C-1/2). Interestingly, Lyz2 is upregulated in microglia of Alzheimer's disease mouse model brains that have been stimulated by specific forms of activity. Lyz1 and Lyz2 are uniquely expressed in microglia, and increased Lyz2 correlates with microglia-mediated beta-amyloid (Abeta) clearance, suggesting that Lysozyme C-1/2 may ly contribute to microglial-clearance of Abeta or act as a marker for certain microglial activity states in the brain.
Clonality	Polyclonal
Description	Boster Bio Anti-Lyz1/2 Antibody Picoband® catalog # A32724. Tested in WB, ELISA applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	E.coli-derived mouse Lyz1/2 recombinant protein (Position: K19-V148). Mouse Lyz1/2 shares 84.6% amino acid (aa) sequence identity with rat Lyz1/2.
Molecular Weight	14 kDa
Reactivity	Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P17897/P08905
Gene Id	17110/17105
Gene Name	Lyz1/2

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Mouse ELISA, 0.1-0.5 ug/ml, -

Reference	1. Cortopassi, G. A., & Wilson, A. C. (1990). Recent origin of the P lysozyme gene in mice. Nucleic acids research, 18(7), 1911. 2. Gao, X., Guo, M., Zhang, Z., Shen, P., Yang, Z., & Zhang, N. (2017). Baicalin promotes the bacteriostatic activity of lysozyme on S. aureus in mammary glands and neutrophilic granulocytes in mice. Oncotarget, 8(12), 19894. 3. Cross, M., & Renkawitz, R. (1990). Repetitive sequence involvement in the duplication and divergence of mouse lysozyme genes. The EMBO joual, 9(4), 1283-1288.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006186-1	A32724	-	100 ug	$370		Add to Cart
BHA21006186-2	A32724-10ug	Sample	10 ug	$99		Add to Cart
BHA21006186-3	A32724-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006186-4	A32724-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006186-5	A32724-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006186-6	A32724-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006186-7	A32724-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006186-8	A32724-FITC	FITC	100 ug	$570		Add to Cart
BHA21006186-9	A32724-HRP	HRP	100 ug	$570		Add to Cart
BHA21006186-10	A32724-APC	APC	100 ug	$670		Add to Cart
BHA21006186-11	A32724-PE	PE	100 ug	$670		Add to Cart
BHA21006186-12	A32724-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006186-13	A32724-carrier-free	carrier-free	100 ug	$370		Add to Cart

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