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Home / Primary Antibodies / Polyclonal Antibodies

Anti-LTK Antibody Picoband®

SKU : BHA21007219

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Mfr.No.	PA1990, PA1990-10ug, PA1990-Biotin, PA1990-Cy3, PA1990-Dylight488, PA1990-Dylight550, PA1990-Dylight594, PA1990-FITC, PA1990-HRP, PA1990-APC, PA1990-PE, PA1990-iFluor647, PA1990-carrier-free
Alternative Names	Leukocyte tyrosine kinase receptor
Background	LTK (Leukocyte Tyrosine Kinase), also known as TYK1, is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. Toyoshima et al. (1993) cloned a set of cDNAs representing differently spliced human LTK mRNAs. Liao et al. (1996) found that the mouse Ltk gene is closely linked to the Tyro3 gene which maps to mouse chromosome 2. Thus, the LTK gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-LTK Antibody catalog # PA1990. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demons
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human LTK.
Isotype	Rabbit IgG
Molecular Weight	85-91 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Leukocyte tyrosine kinase receptor;2.7.10.1;Protein tyrosine kinase 1;LTK;TYK1;
Tissue Specificity	Expressed in non-hematopoietic cell lines and T- and B-cell lines. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P29376
Gene Name	LTK
Sequence	Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Li, N., Nakamura, K., Jiang, Y., Tsurui, H., Matsuoka, S., Abe, M., Ohtsuji, M., Nishimura, H., Kato, K., Kawai, T., Atsumi, T., Koike, T., Shirai, T., Ueno, H., Hirose, S. Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus. Hum. Molec. Genet. 13: 171-179, 2004.<br /><br />2. Liao, X., Zhou, R., Gilbert, D. J., Copeland, N. G., Jenkins, N. A. Receptor tyrosine kinase gene Tyro3 maps to mouse chromosome 2, closely linked to Ltk. Mammalian Genome 7: 395-396, 1996. <br /><br />3. Toyoshima, H., Kozutsumi, H., Maru, Y., Hagiwara, K., Furuya, A., Mioh, H., Hanai, N., Takaku, F., Yazaki, Y., Hirai, H. Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein. Proc. Nat. Acad. Sci. 90: 5404-5408, 1993. <br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007219-1	PA1990	-	100 ug	$370		Add to Cart
BHA21007219-2	PA1990-10ug	Sample	10 ug	$99		Add to Cart
BHA21007219-3	PA1990-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007219-4	PA1990-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007219-5	PA1990-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007219-6	PA1990-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007219-7	PA1990-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007219-8	PA1990-FITC	FITC	100 ug	$570		Add to Cart
BHA21007219-9	PA1990-HRP	HRP	100 ug	$570		Add to Cart
BHA21007219-10	PA1990-APC	APC	100 ug	$670		Add to Cart
BHA21007219-11	PA1990-PE	PE	100 ug	$670		Add to Cart
BHA21007219-12	PA1990-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007219-13	PA1990-carrier-free	carrier-free	100 ug	$370		Add to Cart

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