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Home / Primary Antibodies / Polyclonal Antibodies

Anti-LRRN1 Antibody Picoband®

SKU : BHA21005675

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Mfr.No.	A12074-1, A12074-1-10ug, A12074-1-Biotin, A12074-1-Cy3, A12074-1-Dylight488, A12074-1-Dylight550, A12074-1-Dylight594, A12074-1-FITC, A12074-1-HRP, A12074-1-APC, A12074-1-PE, A12074-1-iFluor647, A12074-1-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	LRRN1 (Leucine-rich repeat neuronal protein 1; NLRR1) is a 95 kDa member of the neuronal LRR family of proteins. It is a cell-surface glycoprotein that is expressed on embryonic motor neurons and somatic myoblasts. Human LRRN1 is 716 amino acids (aa) in length. It is a type I transmembrane protein that contains a 606 aa extracellular region (aa 26-631) and a short 64 aa cytoplasmic tail. The extracellular region shows eleven LRRs (aa 94-384) that mediate protein-protein interactions, one C2-type Ig-like domain and one fibronectin type III domain. There is one potential alteate start site at Met286. Over aa 26-631, human LRRN1 shares 96% aa sequence identity with mouse LRRN1.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-LRRN1 Antibody Picoband® catalog # A12074-1. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human LRRN1 recombinant protein (Position: T74-R655).
Isotype	IgG
Molecular Weight	95 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q6UXK5
Gene Id	57633
Gene Name	LRRN1
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, IHC, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Mouse, Rat<br> Immunohistochemistry, 2-5 ug/ml, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Liu, B., Zhang, Y., Fan, Y., Wang, S., Li, Z., Deng, M., ... & Qu, X. (2019). Leucine?rich repeat neuronal protein?1 suppresses apoptosis of gastric cancer cells through regulation of Fas/FasL. Cancer Science, 110(7), 2145-2155.<br /><br />2. Liao, C. H., Wang, Y. H., Chang, W. W., Yang, B. C., Wu, T. J., Liu, W. L., ... & Yu, J. (2018). Leucine-rich repeat neuronal protein 1 regulates differentiation of embryonic stem cells by post-translational modifications of pluripotency factors. Stem Cells, 36(10), 1514-1524.<br /><br />3. Hossain, M. S., Ozaki, T., Wang, H., Nakagawa, A., Takenobu, H., Ohira, M., ... & Nakagawara, A. (2008). N-MYC promotes cell proliferation through a transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma. Oncogene, 27(46), 6075-6082.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005675-1	A12074-1	-	100 ug	$370		Add to Cart
BHA21005675-2	A12074-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21005675-3	A12074-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005675-4	A12074-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005675-5	A12074-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005675-6	A12074-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005675-7	A12074-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005675-8	A12074-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21005675-9	A12074-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21005675-10	A12074-1-APC	APC	100 ug	$670		Add to Cart
BHA21005675-11	A12074-1-PE	PE	100 ug	$670		Add to Cart
BHA21005675-12	A12074-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005675-13	A12074-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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