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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Lipoamide Dehydrogenase/DLD Antibody Picoband®

SKU : BHA21006810

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Mfr.No.	PA1463, PA1463-10ug, PA1463-Biotin, PA1463-Cy3, PA1463-Dylight488, PA1463-Dylight550, PA1463-Dylight594, PA1463-FITC, PA1463-HRP, PA1463-APC, PA1463-PE, PA1463-iFluor647, PA1463-carrier-free
Alternative Names	Dihydrolipoyl dehydrogenase, mitochondrial
Background	DLD, Dihydrolipoamide dehydrogenase, is a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acid dehydrogenase complex (BCKD). DLD is a flavoprotein enzyme that degrades lipoamide, and produces dihydrolipoamide. The DLD gene contains 14 exons. The gene is localized to 7q31-q32. This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Lipoamide Dehydrogenase/DLD Antibody catalog # PA1463. Tested in IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human DLD, different from the related mouse and rat sequences by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	54 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Dihydrolipoyl dehydrogenase, mitochondrial;1.8.1.4;Dihydrolipoamide dehydrogenase;Glycine cleavage system L protein;DLD;GCSL, LAD, PHE3;
Tissue Specificity	Placenta.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg Thimerosal, 0.01mg NaN3.

Uniprot	P09622
Gene Name	DLD
Sequence	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Subcellular Location	Mitochondrion matrix.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, IHC-F, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat<br> Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Rat, Mouse<br> Immunocytochemistry , 0.5-1ug/ml, Human, -<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br>

Reference	1. Feigenbaum, A. S., Robinson, B. H.The structure of the human dihydrolipoamide dehydrogenase gene (DLD) and its upstream elements.Genomics 17: 376-381, 1993.<br /><br />2. Sakata, Y., Owada, Y., Sato, K., Kojima, K., Hisanaga, K., Shinka, T., Suzuki, Y., Aoki, Y., Satoh, J., Kondo, H., Matsubara, Y., Kure, S.Structure and expression of the glycine cleavage system in rat central nervous system.Molec. Brain Res. 94: 119-130, 2001.<br /><br />3. Scherer, S. W., Otulakowski, G., Robinson, B. H., Tsui, L.-C.Localization of the human dihydrolipoamide dehydrogenase gene (DLD) to 7q31-q32.Cytogenet. Cell Genet. 56: 176-177, 1991.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006810-1	PA1463	-	100 ug	$370		Add to Cart
BHA21006810-2	PA1463-10ug	Sample	10 ug	$99		Add to Cart
BHA21006810-3	PA1463-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006810-4	PA1463-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006810-5	PA1463-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006810-6	PA1463-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006810-7	PA1463-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006810-8	PA1463-FITC	FITC	100 ug	$570		Add to Cart
BHA21006810-9	PA1463-HRP	HRP	100 ug	$570		Add to Cart
BHA21006810-10	PA1463-APC	APC	100 ug	$670		Add to Cart
BHA21006810-11	PA1463-PE	PE	100 ug	$670		Add to Cart
BHA21006810-12	PA1463-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006810-13	PA1463-carrier-free	carrier-free	100 ug	$370		Add to Cart

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