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Home / Primary Antibodies / Polyclonal Antibodies

Anti-LHPP Antibody Picoband®

SKU : BHA21005668

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Mfr.No.	A10687, A10687-10ug, A10687-Biotin, A10687-Cy3, A10687-Dylight488, A10687-Dylight550, A10687-Dylight594, A10687-FITC, A10687-HRP, A10687-APC, A10687-PE, A10687-iFluor647, A10687-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	LHPP, also known as HDHD2B, is a 270 amino acid protein that exists as a homodimer and is a member of the HAD-like hydrolase superfamily. Expressed in liver, kidney and moderately in brain, LHPP is encoded by a gene located on 10, which houses over 1,200 genes and comprises nearly 4.5 % of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-LHPP Antibody Picoband® catalog # A10687. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human LHPP recombinant protein (Position: K6-K270).
Isotype	IgG
Molecular Weight	29 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9H008
Gene Id	64077
Gene Name	LHPP
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Hindupur, S. K., Colombi, M., Fuhs, S. R., Matter, M. S., Guri, Y., Adam, K., Cou, M., Piscuoglio, S., Ng, C. K. Y., Betz, C., Liko, D., Quagliata, L., Moes, S., Jenoe, P., Terracciano, L. M., Heim, M. H., Hunter, T., Hall, M. N. The protein histidine phosphatase LHPP is a tumour suppressor. Nature 555: 678-682, 2018. <br /><br />2. Neff, C. D., Packer, J. C. L., Chen, Y., Potter, J., Riley, R., Davenport, C., DeGrado Warren, J., Jammulapati, S., Bhathena, A., Choi, W. S., Kroeger, P. E., Metzger, R. E., Gutin, A., Skolnick, M. H., Shattuck, D., Katz, D. A. Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression. Molec. Psychiat. 14: 621-630, 2009.<br /><br />3. Yokoi, F., Hiraishi, H., Izuhara, K. Molecular cloning of a cDNA for the human phospholysine phosphohistidine inorganic pyrophosphate phosphatase. J. Biochem. 133: 607-614, 2003.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005668-1	A10687	-	100 ug	$370		Add to Cart
BHA21005668-2	A10687-10ug	Sample	10 ug	$99		Add to Cart
BHA21005668-3	A10687-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005668-4	A10687-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005668-5	A10687-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005668-6	A10687-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005668-7	A10687-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005668-8	A10687-FITC	FITC	100 ug	$570		Add to Cart
BHA21005668-9	A10687-HRP	HRP	100 ug	$570		Add to Cart
BHA21005668-10	A10687-APC	APC	100 ug	$670		Add to Cart
BHA21005668-11	A10687-PE	PE	100 ug	$670		Add to Cart
BHA21005668-12	A10687-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005668-13	A10687-carrier-free	carrier-free	100 ug	$370		Add to Cart

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