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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Leukemia inhibitory factor LIF Antibody Picoband®

SKU : BHA21006891

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Mfr.No.	PA1562, PA1562-10ug, PA1562-Biotin, PA1562-Cy3, PA1562-Dylight488, PA1562-Dylight550, PA1562-Dylight594, PA1562-FITC, PA1562-HRP, PA1562-APC, PA1562-PE, PA1562-iFluor647, PA1562-carrier-free
Alternative Names	Leukemia inhibitory factor
Background	LIF is a pleiotropic cytokine produced at the mateal-fetal interface which has been shown to play an essential role in implantation in mice. LIF is produced in high amounts by the human endometrium and the trophoblast itself, and LIF receptors are present on cytotrophoblast cells. LIF could, thus, play a role in modulating HLA-G production and immune tolerance at the mateal-fetal interface. The gene maps to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Leukemia inhibitory factor LIF Antibody catalog # PA1562. Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of a
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of mouse LIF, identical to the related rat sequence.
Isotype	Rabbit IgG
Molecular Weight	40 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Leukemia inhibitory factor;LIF;Differentiation-stimulating factor;D factor;Lif;
Tissue Specificity	Not abundant; expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P09056
Gene Name	LIF
Sequence	Belongs to the tumor necrosis factor family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat<br>

Reference	1. Bamberger, A.-M., Jenatschke, S., Schulte, H. M., Loning, T., Bamberger, C. M. Leukemia inhibitory factor (LIF) stimulates the human HLA-G promoter in JEG3 choriocarcinoma cells. J. Clin. Endocr. Metab. 85: 3932-3936, 2000.<br /><br />2. Sutherland, G. R., Baker, E., Hyland, V. J., Callen, D. F., Stahl, J., Gough, N. M. The gene for human leukemia inhibitory factor (LIF) maps to 22q12. Leukemia 3: 9-13, 1989.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006891-1	PA1562	-	100 ug	$370		Add to Cart
BHA21006891-2	PA1562-10ug	Sample	10 ug	$99		Add to Cart
BHA21006891-3	PA1562-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006891-4	PA1562-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006891-5	PA1562-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006891-6	PA1562-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006891-7	PA1562-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006891-8	PA1562-FITC	FITC	100 ug	$570		Add to Cart
BHA21006891-9	PA1562-HRP	HRP	100 ug	$570		Add to Cart
BHA21006891-10	PA1562-APC	APC	100 ug	$670		Add to Cart
BHA21006891-11	PA1562-PE	PE	100 ug	$670		Add to Cart
BHA21006891-12	PA1562-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006891-13	PA1562-carrier-free	carrier-free	100 ug	$370		Add to Cart

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