JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-LEF1 Antibody Picoband®

SKU : BHA21003357

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	A00605-2, A00605-2-10ug, A00605-2-Biotin, A00605-2-Cy3, A00605-2-Dylight488, A00605-2-Dylight550, A00605-2-Dylight594, A00605-2-FITC, A00605-2-HRP, A00605-2-APC, A00605-2-PE, A00605-2-iFluor647, A00605-2-carrier-free
Alternative Names	ADAM metallopeptidase domain 17
Background	Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-LEF1 Antibody Picoband® catalog # A00605-2. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, includi
Host	Rabbit
Immunogen Region	E.coli-derived human LEF1 recombinant protein (Position: D14-H274).
Isotype	Rabbit IgG
Molecular Weight	58 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; 3.4.24.86; Snake venom-like protease; TNF-alpha convertase; TNF-alpha-converting enzyme; CD156b; ADAM17; CSVP, TACE;
Tissue Specificity	Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Uniprot	Q9UJU2
Gene Id	51176
Gene Name	LEF1
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. de Lau, W., Clevers, H. LEF1 tus over a new leaf. Nature Genet. 28: 3-5, 2001.<br /><br />2. Driessens, G., Zheng, Y., Gajewski, T. F. Beta-catenin does not regulate memory T cell phenotype. (Letter) Nature Med. 16: 513-514, 2010. <br /><br />3. Galceran, J., Sustmann, C., Hsu, S.-C., Folberth, S., Grosschedl, R. LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis. Genes Dev. 18: 2718-2723, 2004.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003357-1	A00605-2	-	100 ug	$370		Add to Cart
BHA21003357-2	A00605-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003357-3	A00605-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003357-4	A00605-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003357-5	A00605-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003357-6	A00605-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003357-7	A00605-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003357-8	A00605-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003357-9	A00605-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003357-10	A00605-2-APC	APC	100 ug	$670		Add to Cart
BHA21003357-11	A00605-2-PE	PE	100 ug	$670		Add to Cart
BHA21003357-12	A00605-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003357-13	A00605-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.