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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Kv1.4/KCNA4 Antibody Picoband®

SKU : BHA21000709

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Mfr.No.	PB9807, PB9807-10ug, PB9807-Biotin, PB9807-Cy3, PB9807-Dylight488, PB9807-Dylight550, PB9807-Dylight594, PB9807-FITC, PB9807-HRP, PB9807-APC, PB9807-PE, PB9807-iFluor647, PB9807-carrier-free
Alternative Names	Potassium voltage-gated channel subfamily A member 4
Background	Potassium voltage-gated channel subfamily A member 4, also known as Kv1.4 or PCN2, is a protein that in humans is encoded by the KCNA4 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It is mapped to 11p14.1. KCNA4 belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential. KCNA4 also contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. This gene has been shown to interact with DLG4, KCNA2 and DLG1.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Kv1.4/KCNA4 Antibody Picoband® catalog # PB9807. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alteat
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.4, different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	73 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Potassium voltage-gated channel subfamily A member 4;HPCN2;Voltage-gated K (+) channel HuKII ;Voltage-gated potassium channel HBK4;Voltage-gated potassium channel HK1 ;Voltage-gated potassium channel subunit Kv1.4;KCNA4;KCNA4L;
Tissue Specificity	Detected in heart ventricle. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P22459
Gene Id	3739
Gene Name	KCNA4
Subcellular Location	Cell membrane ; Multi-pass membrane protein . Cell projection, axon .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Weste blot, 0.1-0.5ug/ml, Human

Reference	1. "Entrez Gene: KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4". 2. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "Inteational Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev 57 (4): 473508. 3. Philipson LH, Schaefer K, LaMendola J, Bell GI, Steiner DF (Feb 1991)."Sequence of a human fetal skeletal muscle potassium channel cDNA related to RCK4". Nucleic Acids Res 18 (23): 7160.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000709-1	PB9807	100 ug	-	$370		Add to Cart
BHA21000709-2	PB9807-10ug	10 ug	Sample	$99		Add to Cart
BHA21000709-3	PB9807-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000709-4	PB9807-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000709-5	PB9807-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000709-6	PB9807-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000709-7	PB9807-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000709-8	PB9807-FITC	100 ug	FITC	$570		Add to Cart
BHA21000709-9	PB9807-HRP	100 ug	HRP	$570		Add to Cart
BHA21000709-10	PB9807-APC	100 ug	APC	$670		Add to Cart
BHA21000709-11	PB9807-PE	100 ug	PE	$670		Add to Cart
BHA21000709-12	PB9807-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000709-13	PB9807-carrier-free	100 ug	carrier-free	$370		Add to Cart

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