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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Kv1.1 potassium channel/KCNA1 Antibody Picoband®

SKU : BHA21001926

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Mfr.No.	A01813-1, A01813-1-10ug, A01813-1-Biotin, A01813-1-Cy3, A01813-1-Dylight488, A01813-1-Dylight550, A01813-1-Dylight594, A01813-1-FITC, A01813-1-HRP, A01813-1-APC, A01813-1-PE, A01813-1-iFluor647, A01813-1-carrier-free
Alternative Names	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
Background	Potassium voltage-gated channel subfamily A member 1, also known as Kv1.1, is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. It is mapped to 12p13.32. The protein functions as a potassium selective channel through which the potassium ion may pass through in consensus with the electrochemical gradient. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Kv1.1 potassium channel/KCNA1 Antibody Picoband® catalog # A01813-1. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney (PubMed:19903818). Contributes to the regulation of the membrane potentia
Host	Rabbit
Immunogen Region	E. coli-derived human KCNA1 recombinant protein (Position: E7-N477).
Isotype	Rabbit IgG
Molecular Weight	56 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Potassium voltage-gated channel subfamily A member 1; Voltage-gated K (+) channel HuKI
Tissue Specificity	Detected adjacent to nodes of Ranvier in juxtaparanodal zones in spinal cord nerve fibers, but also in paranodal regions in some myelinated spinal cord axons (at protein level) (PubMed:11086297). Detected in the islet of Langerhans (PubMed:21483673).
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q09470
Gene Id	3736
Gene Name	KCNA1
Subcellular Location	Cell membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Rat<br> Immunofluorescence, 5ug/ml, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Albrecht B, Weber K, Pongs O (1995). "Characterization of a voltage-activated K-channel gene cluster on human chromosome 12p13". Recept. Channels 3 (3): 21320.<br /><br />2. Curran ME, Landes GM, Keating MT (1992). "Molecular cloning, characterization, and genomic localization of a human potassium channel gene". Genomics 12 (4): 72937.<br /><br />3. "Entrez Gene: KCNA1 potassium voltage-gated channel".

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001926-1	A01813-1	100 ug	-	$370		Add to Cart
BHA21001926-2	A01813-1-10ug	10 ug	Sample	$99		Add to Cart
BHA21001926-3	A01813-1-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001926-4	A01813-1-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001926-5	A01813-1-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001926-6	A01813-1-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001926-7	A01813-1-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001926-8	A01813-1-FITC	100 ug	FITC	$570		Add to Cart
BHA21001926-9	A01813-1-HRP	100 ug	HRP	$570		Add to Cart
BHA21001926-10	A01813-1-APC	100 ug	APC	$670		Add to Cart
BHA21001926-11	A01813-1-PE	100 ug	PE	$670		Add to Cart
BHA21001926-12	A01813-1-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001926-13	A01813-1-carrier-free	100 ug	carrier-free	$370		Add to Cart

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