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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Krueppel-like factor 4 KLF4 Antibody Picoband®

SKU : BHA21007397

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Mfr.No.	PA2211, PA2211-10ug, PA2211-Biotin, PA2211-Cy3, PA2211-Dylight488, PA2211-Dylight550, PA2211-Dylight594, PA2211-FITC, PA2211-HRP, PA2211-APC, PA2211-PE, PA2211-iFluor647, PA2211-carrier-free
Alternative Names	Krueppel-like factor 4
Background	Kruppel-like factor 4, also known as EZF or GKLF, is a protein that in humans is encoded by the KLF4 gene. This gene is mapped to 9q31.2. KLF4 gene encodes a member of the Kruppel family of transcription factors. This gene plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. It is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. This gene involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Krueppel-like factor 4 KLF4 Antibody catalog # PA2211. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryo
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human KLF4, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	47 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Krueppel-like factor 4;Epithelial zinc finger protein EZF;Gut-enriched krueppel-like factor;KLF4;EZF, GKLF;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	O43474
Gene Name	KLF4
Sequence	Belongs to the krueppel C2H2-type zinc-finger protein family.
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Western blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Moore, D. L., Blackmore, M. G., Hu, Y., Kaestner, K. H., Bixby, J. L., Lemmon, V. P., Goldberg, J. L. KLF family members regulate intrinsic axon regeneration ability. Science 326: 298-301, 2009.<br /><br />2. Patel, S., Xi, Z. F., Seo, E. Y., McGaughey, D., Segre, J. A. Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc. Nat. Acad. Sci. 103: 18668-18673, 2006.<br /><br />3. Wang, H., Yang, L., Jamaluddin, M. S., Boyd, D. D. The Kruppel-like KLF4 transcription factor, a novel regulator of urokinase receptor expression, drives synthesis of this binding site in colonic crypt luminal surface epithelial cells. J. Biol. Chem. 279: 22674-22683, 2004.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007397-1	PA2211	-	100 ug	$370		Add to Cart
BHA21007397-2	PA2211-10ug	Sample	10 ug	$99		Add to Cart
BHA21007397-3	PA2211-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007397-4	PA2211-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007397-5	PA2211-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007397-6	PA2211-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007397-7	PA2211-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007397-8	PA2211-FITC	FITC	100 ug	$570		Add to Cart
BHA21007397-9	PA2211-HRP	HRP	100 ug	$570		Add to Cart
BHA21007397-10	PA2211-APC	APC	100 ug	$670		Add to Cart
BHA21007397-11	PA2211-PE	PE	100 ug	$670		Add to Cart
BHA21007397-12	PA2211-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007397-13	PA2211-carrier-free	carrier-free	100 ug	$370		Add to Cart

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