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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Krueppel-like factor 3 KLF3 Antibody Picoband®

SKU : BHA21007143

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Mfr.No.	PA1888, PA1888-10ug, PA1888-Biotin, PA1888-Cy3, PA1888-Dylight488, PA1888-Dylight550, PA1888-Dylight594, PA1888-FITC, PA1888-HRP, PA1888-APC, PA1888-PE, PA1888-iFluor647, PA1888-carrier-free
Alternative Names	Krueppel-like factor 3
Background	KLF3 (Krueppel-like factor 3) is a protein that in humans is encoded by the KLF3 gene. It is also known as BKLF (Basic kruppel-like factor). KLF3 is a member of the Krüppel-like factors family of transcription factors. KLF3 primarily represses transcription through the transcriptional corepressor C-terminal binding protein (CtBP). Suske et al. (2005) stated that the human KLF3 gene maps to chromosome 4p14, and the mouse Klf3 gene maps to chromosome 5C3.3. Suske et al. (2005) stated that the human and mouse KLF3 proteins contain 345 and 344 amino acids, respectively. Both have a characteristic zinc finger domain, but lack the N-terminal buttonhead box found in related SP transcription factors. The repression mediated through KLF3 is also partially dependent on the sumoylation of its K10 and K197. Within KLF3's C-terminal, which is highly conserved throughout the KLF family, resides three C2H2 zinc fingers that preferentially bind the site NRG GNG NGR.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Krueppel-like factor 3 KLF3 Antibody catalog # PA1888. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human KLF3, different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	18 kDa
Reactivity	Rat, Mouse, Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Krueppel-like factor 3;Basic krueppel-like factor;CACCC-box-binding protein BKLF;TEF-2;KLF3;BKLF;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P57682
Gene Name	KLF3
Sequence	Belongs to the krueppel C2H2-type zinc-finger protein family.
Subcellular Location	Nucleus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1. Suske, G., Bruford, E., Philipsen, S.Mammalian SP/KLF transcription factors: bring in the family.Genomics 85: 551-556, 2005.<br /><br />2. Tuer, Jeremy; Nicholas Hannah, Bishop David, Matthews Jacqueline M, Crossley Merlin "The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2". J. Biol. Chem. (United States) 278 (15): 1278695. 2003<br /><br />3. Wang MJ, Qu XH, Wang LS, et al.. "(cDNA cloning, subcellular localization and tissue expression of a new human Krüppel-like transcription factor: human basic Krüppel-like factor (hBKLF))". Yi Chuan Xue Bao 30 (1): 19. 2003.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007143-1	PA1888	-	100 ug	$370		Add to Cart
BHA21007143-2	PA1888-10ug	Sample	10 ug	$99		Add to Cart
BHA21007143-3	PA1888-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007143-4	PA1888-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007143-5	PA1888-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007143-6	PA1888-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007143-7	PA1888-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007143-8	PA1888-FITC	FITC	100 ug	$570		Add to Cart
BHA21007143-9	PA1888-HRP	HRP	100 ug	$570		Add to Cart
BHA21007143-10	PA1888-APC	APC	100 ug	$670		Add to Cart
BHA21007143-11	PA1888-PE	PE	100 ug	$670		Add to Cart
BHA21007143-12	PA1888-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007143-13	PA1888-carrier-free	carrier-free	100 ug	$370		Add to Cart

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