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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Kininogen 1/KNG1 Antibody Picoband®

SKU : BHA21000211

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Mfr.No.	PB9278, PB9278-10ug, PB9278-Biotin, PB9278-Cy3, PB9278-Dylight488, PB9278-Dylight550, PB9278-Dylight594, PB9278-FITC, PB9278-HRP, PB9278-APC, PB9278-PE, PB9278-iFluor647, PB9278-carrier-free
Alternative Names	Kininogen-1
Background	Kininogen-1 (KNG1), also known as BDK or bradykinin is a protein that in humans is encoded by the KNG1 gene. It is mapped to 3q27.3. The KNG1 gene uses alteative splicing to generate two different proteins high molecular - weight kininogen (HMWK) and low - molecular- weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, KNG1, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. In addition to that, KNG1 is a constituent of the blood coagulation system as well as the kinin-kallikrein system.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Kininogen 1/KNG1 Antibody Picoband® catalog # PB9278. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	(1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin- induced
Host	Rabbit
Immunogen Region	E.coli-derived human Kininogen 1 recombinant protein (Position: Q19-N210). Human Kininogen 1 shares 63% and 66% amino acid (aa) sequence identity with mouse and rat Kininogen 1, respectively.
Isotype	Rabbit IgG
Molecular Weight	72 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Kininogen-1;Alpha-2-thiol proteinase inhibitor;Fitzgerald factor;High molecular weight kininogen;HMWK;Williams-Fitzgerald-Flaujeac factor;Kininogen-1 heavy chain;T-kinin;Ile-Ser-Bradykinin;Bradykinin;Kallidin I;Lysyl-bradykinin;Kallidin II;Kininogen-1 light chain;Low molecular weight growth-promoting factor;KNG1;BDK, KNG;
Tissue Specificity	Secreted in plasma. T-kinin is detected in malignant ovarian, colon and breast carcinomas, but not in benign tumors. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P01042
Gene Id	3827
Gene Name	KNG1
Sequence	Contains 3 cystatin kininogen-type domains.
Subcellular Location	Secreted, extracellular space.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human

Reference	1. "Entrez Gene: kininogen 1" 2. Fong, D., Smith, D. I., Hsieh, W.-T. The human kininogen gene (KNG) mapped to chromosome 3q26-qter by analysis of somatic cell hybrids using the polymerase chain reaction. Hum. Genet. 87: 189-192, 1991.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000211-1	PB9278	100 ug	-	$370		Add to Cart
BHA21000211-2	PB9278-10ug	10 ug	Sample	$99		Add to Cart
BHA21000211-3	PB9278-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000211-4	PB9278-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000211-5	PB9278-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000211-6	PB9278-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000211-7	PB9278-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000211-8	PB9278-FITC	100 ug	FITC	$570		Add to Cart
BHA21000211-9	PB9278-HRP	100 ug	HRP	$570		Add to Cart
BHA21000211-10	PB9278-APC	100 ug	APC	$670		Add to Cart
BHA21000211-11	PB9278-PE	100 ug	PE	$670		Add to Cart
BHA21000211-12	PB9278-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000211-13	PB9278-carrier-free	100 ug	carrier-free	$370		Add to Cart

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