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Home / Primary Antibodies / Polyclonal Antibodies

Anti-KIAA0652/ATG13 Antibody Picoband®

SKU : BHA21000376

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Mfr.No.	PB9480, PB9480-10ug, PB9480-Biotin, PB9480-Cy3, PB9480-Dylight488, PB9480-Dylight550, PB9480-Dylight594, PB9480-FITC, PB9480-HRP, PB9480-APC, PB9480-PE, PB9480-iFluor647, PB9480-carrier-free
Alternative Names	Autophagy-related protein 13
Background	Autophagy-related protein 13, also known as ATG13, is a protein that in humans is encoded by the KIAA0652 gene. ATG13 is an autophagy factor required for phagosome formation. It is located on 11p11.2. And ATG13 is a target of the TOR kinase signaling pathway that regulates autophagy through phosphorylation of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-KIAA0652/ATG13 Antibody Picoband® catalog # PB9480. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 comp
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human KIAA0652, identical to the related mouse sequence.
Isotype	Rabbit IgG
Molecular Weight	56 kDa
Reactivity	Human, Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Autophagy-related protein 13;ATG13;KIAA0652;
Tissue Specificity	Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	O75143
Gene Id	9776
Gene Name	ATG13
Sequence	Belongs to the ATG13 metazoan family.
Subcellular Location	Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse

Reference	1. "Entrez Gene: KIAA0652". 2. Chan EY, Longatti A, McKnight NC, Tooze SA (January 2009)."Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism". Mol. Cell. Biol. 29 (1): 15771. 3. Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N (April 2009). "Nutrient-dependent mTORC1 Association with the ULK1Atg13FIP200 Complex Required for Autophagy". Mol. Biol. Cell 20 (7): 198191. 4. Mercer CA, Kaliappan A, Dennis PB (July 2009). "A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy". Autophagy 5 (5): 64962.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000376-1	PB9480	100 ug	-	$370		Add to Cart
BHA21000376-2	PB9480-10ug	10 ug	Sample	$99		Add to Cart
BHA21000376-3	PB9480-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000376-4	PB9480-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000376-5	PB9480-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000376-6	PB9480-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000376-7	PB9480-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000376-8	PB9480-FITC	100 ug	FITC	$570		Add to Cart
BHA21000376-9	PB9480-HRP	100 ug	HRP	$570		Add to Cart
BHA21000376-10	PB9480-APC	100 ug	APC	$670		Add to Cart
BHA21000376-11	PB9480-PE	100 ug	PE	$670		Add to Cart
BHA21000376-12	PB9480-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000376-13	PB9480-carrier-free	100 ug	carrier-free	$370		Add to Cart

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