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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Ki67/MKI67 Antibody Picoband®

SKU : BHA21007488

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Mfr.No.	PB9026, PB9026-10ug, PB9026-Biotin, PB9026-Cy3, PB9026-Dylight488, PB9026-Dylight550, PB9026-Dylight594, PB9026-FITC, PB9026-HRP, PB9026-APC, PB9026-PE, PB9026-iFluor647, PB9026-carrier-free
Alternative Names	Antigen KI-67
Background	Ki-67 (Proliferation-related Ki-67 antigen), also known as MKI67 or KIA, is a protein that in humans is encoded by the MKI67 gene. From study of a panel of human-rodent somatic cell hybrids, it has been demonstrated that a gene involved in the expression of the MKI67 antigen is located on chromosome 10. By in situ hybridization, Fonatsch et al. (1991) regionalized the MKI67 gene to chromosome 10q25-qter. By FISH, Traut et al. (1998) mapped the mouse Mki67 gene to chromosome 7F3-F5. Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Ki67/MKI67 Antibody Picoband® catalog # PB9026. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Thought to be required for maintaining cell proliferation.
Host	Rabbit
Immunogen Region	E.coli-derived human Ki67 recombinant protein (Position: K2860-I3256).
Isotype	Rabbit IgG
Molecular Weight	358 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Antigen KI-67;MKI67;
Tissue Specificity	Released primarily from activated T lymphocytes.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P46013
Gene Id	4288
Gene Name	MKI67
Sequence	Contains 1 FHA domain.
Subcellular Location	Nucleus . Nucleus, nucleolus . Chromosome . Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br> Immunocytochemistry , 0.5-1ug/ml, Human, -<br> Immunofluorescence, 5ug/ml, Human<br>

Reference	1. Fonatsch, C., Duchrow, M., Rieder, H., Schluter, C., Gerdes, J. Assignment of the human Ki-67 gene (MKI67) to 10q25-qter. Genomics 11: 476-477, 1991.<br /><br />2. Schonk, D. M., Kuijpers, H. J. H., vanDrunen, E., vanDalen, C. H., Geurts van Kessel, A. H. M., Verheijen, R., Ramaekers, F. C. S. Assignment of the gene(s) involved in the expression of the proliferation-related Ki-67 antigen to human chromosome 10. Hum. Genet. 83: 297-299, 1989.<br /><br />3. Traut, W., Scholzen, T., Winking, H., Kubbutat, M. H. G., Gerdes, J. Assignment of the murine Ki-67 gene (Mki67) to chromosome band 7F3-F5 by in situ hybridization. Cytogenet. Cell Genet. 83: 12-13, 1998.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007488-1	PB9026	-	100 ug	$370		Add to Cart
BHA21007488-2	PB9026-10ug	Sample	10 ug	$99		Add to Cart
BHA21007488-3	PB9026-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007488-4	PB9026-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007488-5	PB9026-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007488-6	PB9026-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007488-7	PB9026-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007488-8	PB9026-FITC	FITC	100 ug	$570		Add to Cart
BHA21007488-9	PB9026-HRP	HRP	100 ug	$570		Add to Cart
BHA21007488-10	PB9026-APC	APC	100 ug	$670		Add to Cart
BHA21007488-11	PB9026-PE	PE	100 ug	$670		Add to Cart
BHA21007488-12	PB9026-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007488-13	PB9026-carrier-free	carrier-free	100 ug	$370		Add to Cart

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