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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Keratocan Antibody Picoband®

SKU : BHA21000554

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Mfr.No.	PB9653, PB9653-10ug, PB9653-Biotin, PB9653-Cy3, PB9653-Dylight488, PB9653-Dylight550, PB9653-Dylight594, PB9653-FITC, PB9653-HRP, PB9653-APC, PB9653-PE, PB9653-iFluor647, PB9653-carrier-free
Alternative Names	Keratocan
Background	Keratocan (KTN), also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. It is mapped to 12q22. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in coeal transparency. Defects in this gene are a cause of autosomal recessive coea plana 2 (CNA2). Keratan sulfate proteoglycans (KSPGs) are members of the small leucine-rich proteoglycan (SLRP) family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of the coea.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Keratocan Antibody Picoband® catalog # PB9653. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May be important in developing and maintaining coeal transparency and for the structure of the stromal matrix.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Keratocan, different from the related mouse sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Human, Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Keratocan;KTN;Keratan sulfate proteoglycan keratocan;KERA;SLRR2B;
Tissue Specificity	Coea. Increased expression in the stroma of keratoconus coeas. Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	O60938
Gene Id	11081
Gene Name	KERA
Sequence	Contains 1 HMG box DNA-binding domain.
Subcellular Location	Secreted, extracellular space, extracellular matrix .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse

Reference	1. "Entrez Gene: KERA keratocan". 2. Pellegata NS, Dieguez-Lucena JL, Joensuu T, Lau S, Montgomery KT, Krahe R, Kivela T, Kucherlapati R, Forsius H, de la Chapelle A (Jun 2000). "Mutations in KERA, encoding keratocan, cause coea plana". Nat Genet 25(1): 915. 3. Tasheva ES, Funderburgh JL, Funderburgh ML, Corpuz LM, Conrad GW (Jan 2000). "Structure and sequence of the gene encoding human keratocan". DNA Seq 10 (1): 6774.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000554-1	PB9653	100 ug	-	$370		Add to Cart
BHA21000554-2	PB9653-10ug	10 ug	Sample	$99		Add to Cart
BHA21000554-3	PB9653-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000554-4	PB9653-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000554-5	PB9653-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000554-6	PB9653-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000554-7	PB9653-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000554-8	PB9653-FITC	100 ug	FITC	$570		Add to Cart
BHA21000554-9	PB9653-HRP	100 ug	HRP	$570		Add to Cart
BHA21000554-10	PB9653-APC	100 ug	APC	$670		Add to Cart
BHA21000554-11	PB9653-PE	100 ug	PE	$670		Add to Cart
BHA21000554-12	PB9653-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000554-13	PB9653-carrier-free	100 ug	carrier-free	$370		Add to Cart

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