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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Interleukin-4 IL4 Antibody Picoband®

SKU : BHA21006866

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Mfr.No.	PA1529, PA1529-10ug, PA1529-Biotin, PA1529-Cy3, PA1529-Dylight488, PA1529-Dylight550, PA1529-Dylight594, PA1529-FITC, PA1529-HRP, PA1529-APC, PA1529-PE, PA1529-iFluor647, PA1529-carrier-free
Alternative Names	Interleukin-4
Background	Interleukin-4 (IL-4), also knowns as a B-cell stimulatory factor1 (BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells. The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-ed immunosurveillance in vivo, in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis. The mouse and human genes and their protein products show structural and functional similarities. The human IL-4 gene, which occurs as a single copy in the haploid genome, is mapped on chromosome 5.2 The standard product used in this kit is recombinant human IL-4, consisting of 130 amino acids with the molecular mass of 14KDa.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Interleukin-4 IL4 Antibody catalog # PA1529. Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface express
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL-4.
Isotype	Rabbit IgG
Molecular Weight	37 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-4;IL-4;B-cell IgG differentiation factor;B-cell growth factor 1;B-cell stimulatory factor 1;BSF-1;IGG1 induction factor;Lymphocyte stimulatory factor 1;Il4;Il-4;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P07750
Gene Name	IL4
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse<br>

Reference	1. Prokopchuk, O.; Liu, Y.; Henne-Bruns, D.; Komann, M. Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions. Br J Cancer.2005 Mar 14;92(5):921-8.<br /><br />2. Arai, N.; Nomura, D.; Villaret, D.; DeWaal Malefijt, R.; Seiki, M.; Yoshida, M.; Minoshima, S.; Fukuyama, R.; Maekawa, M.; Kudoh, J.; Shimizu, N.; Yokota, K.; Abe, E.; Yokota, T.; Takebe, Y.; Arai, K. Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression. J. Immun. 142: 274-282, 1989.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006866-1	PA1529	-	100 ug	$370		Add to Cart
BHA21006866-2	PA1529-10ug	Sample	10 ug	$99		Add to Cart
BHA21006866-3	PA1529-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006866-4	PA1529-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006866-5	PA1529-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006866-6	PA1529-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006866-7	PA1529-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006866-8	PA1529-FITC	FITC	100 ug	$570		Add to Cart
BHA21006866-9	PA1529-HRP	HRP	100 ug	$570		Add to Cart
BHA21006866-10	PA1529-APC	APC	100 ug	$670		Add to Cart
BHA21006866-11	PA1529-PE	PE	100 ug	$670		Add to Cart
BHA21006866-12	PA1529-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006866-13	PA1529-carrier-free	carrier-free	100 ug	$370		Add to Cart

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