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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Interleukin-3 IL3 Antibody Picoband®

SKU : BHA21007013

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Mfr.No.	PA1728, PA1728-10ug, PA1728-Biotin, PA1728-Cy3, PA1728-Dylight488, PA1728-Dylight550, PA1728-Dylight594, PA1728-FITC, PA1728-HRP, PA1728-APC, PA1728-PE, PA1728-iFluor647, PA1728-carrier-free
Alternative Names	Interleukin-3
Background	Interleukin 3, also known as IL-3, is a protein that in humans is encoded by the IL3 gene. Ot is mapped to 5q31.1. IL-3 is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells or, with the addition of IL-7, into lymphoid progenitor cells. In addition, IL-3 stimulates proliferation of all cells in the myeloid lineage (granulocytes, monocytes, and dendritic cells), in conjunction with other cytokines, e.g., Erythropoietin (EPO), Granulocyte macrophage colony-stimulating factor (GM-CSF), and IL-6. IL-3 is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Interleukin-3 IL3 Antibody catalog # PA1728. Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of mouse IL-3.
Isotype	Rabbit IgG
Molecular Weight	14 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-3;IL-3;Hematopoietic growth factor;Mast cell growth factor;MCGF;Multipotential colony-stimulating factor;P-cell-stimulating factor;Il3;Csfmu, Il-3;
Tissue Specificity	Activated T-cells, mast cells, natural killer cells.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P01586
Gene Name	IL3
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse<br>

Reference	1. Le Beau, M. M.; Epstein, N. D.; O'Brien, S. J.; Nienhuis, A. W.; Yang, Y.-C.; Clark, S. C.; Rowley, J. D. The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. Proc. Nat. Acad. Sci. 84: 5913-5917, 1987.<br /><br />2. Clark-Lewis, I.; Aebersold, R.; Ziltener, H.; Schrader, J. W.; Hood, L. E.; Kent, S. B. H. Automated chemical synthesis of a protein growth factor for hemopoietic cells, interleukin-3. Science 231: 134-139, 1986.<br /><br />3. Fung, M. C.; Hapel, A. J.; Ymer, S.; Cohen, D. R.; Johnson, R. M.; Campbell, H. D.; Young, I. G. Molecular cloning of cDNA for murine interleukin-3. Nature 307: 233-237, 1984.<br /><br />4. Ihle, J. N.; Silver, J.; Kozak, C. A. Genetic mapping of the mouse interleukin 3 gene to chromosome 11. J. Immun. 138: 3051-3054, 1987.<br /><br />5. Yang, Y.-C.; Kovacic, S.; Kriz, R.; Wolf, S.; Clark, S. C.; Wellems, T. E.; Nienhuis, A.; Epstein, N. The human genes for GM-CSF and IL3 are closely linked in tandem on chromosome 5. Blood 71: 958-961, 1988.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007013-1	PA1728	-	100 ug	$370		Add to Cart
BHA21007013-2	PA1728-10ug	Sample	10 ug	$99		Add to Cart
BHA21007013-3	PA1728-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007013-4	PA1728-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007013-5	PA1728-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007013-6	PA1728-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007013-7	PA1728-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007013-8	PA1728-FITC	FITC	100 ug	$570		Add to Cart
BHA21007013-9	PA1728-HRP	HRP	100 ug	$570		Add to Cart
BHA21007013-10	PA1728-APC	APC	100 ug	$670		Add to Cart
BHA21007013-11	PA1728-PE	PE	100 ug	$670		Add to Cart
BHA21007013-12	PA1728-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007013-13	PA1728-carrier-free	carrier-free	100 ug	$370		Add to Cart

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