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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Interleukin-10 IL10 Antibody Picoband®

SKU : BHA21006591

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Mfr.No.	RP1016, RP1016-10ug, RP1016-Biotin, RP1016-Cy3, RP1016-Dylight488, RP1016-Dylight550, RP1016-Dylight594, RP1016-FITC, RP1016-HRP, RP1016-APC, RP1016-PE, RP1016-iFluor647, RP1016-carrier-free
Alternative Names	Interleukin-10
Background	Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Interleukin-10 IL10 Antibody catalog # RP1016. Tested in ELISA, IHC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. .
Host	Rabbit
Immunogen Region	E. coli-derived rat IL-10 recombinant protein (Position: S19-N178).
Isotype	Rabbit IgG
Molecular Weight	21 kDa
Reactivity	Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-10;IL-10;Cytokine synthesis inhibitory factor;CSIF;Il10;Il-10;
Tissue Specificity	Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P29456
Gene Name	IL10
Sequence	Belongs to the IL-10 family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Rat, By Heat <br>ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). "Mapping of the human IL10 gene and further characterization of the 5' flanking sequence".

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006591-1	RP1016	-	100 ug	$370		Add to Cart
BHA21006591-2	RP1016-10ug	Sample	10 ug	$99		Add to Cart
BHA21006591-3	RP1016-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006591-4	RP1016-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006591-5	RP1016-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006591-6	RP1016-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006591-7	RP1016-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006591-8	RP1016-FITC	FITC	100 ug	$570		Add to Cart
BHA21006591-9	RP1016-HRP	HRP	100 ug	$570		Add to Cart
BHA21006591-10	RP1016-APC	APC	100 ug	$670		Add to Cart
BHA21006591-11	RP1016-PE	PE	100 ug	$670		Add to Cart
BHA21006591-12	RP1016-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006591-13	RP1016-carrier-free	carrier-free	100 ug	$370		Add to Cart

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