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Home / Primary Antibodies / Polyclonal Antibodies

Anti-INDOL1/IDO2 Antibody Picoband®

SKU : BHA21006926

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Mfr.No.	PA1612, PA1612-10ug, PA1612-Biotin, PA1612-Cy3, PA1612-Dylight488, PA1612-Dylight550, PA1612-Dylight594, PA1612-FITC, PA1612-HRP, PA1612-APC, PA1612-PE, PA1612-iFluor647, PA1612-carrier-free
Alternative Names	Indoleamine 2,3-dioxygenase 2
Background	IDO2 (Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan (D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-INDOL1/IDO2 Antibody catalog # PA1612. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human INDOL1.
Isotype	Rabbit IgG
Molecular Weight	47 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Indoleamine 2,3-dioxygenase 2;IDO-2;1.13.11.-;Indoleamine 2,3-dioxygenase-like protein 1;Indoleamine-pyrrole 2,3-dioxygenase-like protein 1;IDO2;INDOL1;
Tissue Specificity	Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg Thimerosal, 0.01mg NaN3.

Uniprot	Q6ZQW0
Gene Name	IDO2
Sequence	Belongs to the indoleamine 2,3-dioxygenase family.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Ball, H. J., Sanchez-Perez, A., Weiser, S., Austin, C. J. D., Astelbauer, F., Miu, J., McQuillan, J. A., Stocker, R., Jermin, L. S., Hunt, N. H. Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice. Gene 396: 203-213, 2007.<br /><br />2. Metz, R., DuHadaway, J. B., Kamasani, U., Laury-Kleintop, L., Muller, A. J., Prendergast, G. C. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res. 67: 7082-7087, 2007.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006926-1	PA1612	-	100 ug	$370		Add to Cart
BHA21006926-2	PA1612-10ug	Sample	10 ug	$99		Add to Cart
BHA21006926-3	PA1612-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006926-4	PA1612-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006926-5	PA1612-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006926-6	PA1612-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006926-7	PA1612-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006926-8	PA1612-FITC	FITC	100 ug	$570		Add to Cart
BHA21006926-9	PA1612-HRP	HRP	100 ug	$570		Add to Cart
BHA21006926-10	PA1612-APC	APC	100 ug	$670		Add to Cart
BHA21006926-11	PA1612-PE	PE	100 ug	$670		Add to Cart
BHA21006926-12	PA1612-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006926-13	PA1612-carrier-free	carrier-free	100 ug	$370		Add to Cart

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