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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL8/CXCL8 Antibody Picoband®

SKU : BHA21000523

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Mfr.No.	PB9621, PB9621-10ug, PB9621-Biotin, PB9621-Cy3, PB9621-Dylight488, PB9621-Dylight550, PB9621-Dylight594, PB9621-FITC, PB9621-HRP, PB9621-APC, PB9621-PE, PB9621-iFluor647, PB9621-carrier-free
Alternative Names	Interleukin-8
Background	Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene. Interleukin-8 (IL8) is a member of the CXC chemokine family. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. The genes for IL8 have been co-localized on a 335-kb genomic fragment.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IL8/CXCL8 Antibody Picoband® catalog # PB9621. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8 (6-77) has a 5-10-fold hi
Host	Rabbit
Immunogen Region	E. coli-derived human IL-8 recombinant protein (Position: A23-S99).
Isotype	Rabbit IgG
Molecular Weight	11 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-8;IL-8;C-X-C motif chemokine 8;Chemokine (C-X-C motif) ligand 8;Emoctakin;Granulocyte chemotactic protein 1;GCP-1;Monocyte-derived neutrophil chemotactic factor;MDNCF;Monocyte-derived neutrophil-activating peptide;MONAP;Neutrophil-activating protein 1;NAP-1;Protein 3-10C;T-cell chemotactic factor;MDNCF-a;GCP/IL-8 protein IV;IL8/NAP1 form I;Interleukin-8; (Ala-IL-8)77;GCP/IL-8 protein II;IL-8 (1-77);IL8/NAP1 form II;MDNCF-b;IL-8 (5-77);IL-8 (6-77); (Ser-IL-8)72;GCP/IL-8 protein I;IL8/NAP1 form III;Lymphocyte-derived neutrophil-activating factor;LYNAP;MDNCF-c;Neutrophil-activating factor;NAF;IL-8 (7-77);GCP/IL-8 protein V;IL8/NAP1 form IV;IL-8 (8-77);GCP/IL-8 protein VI;IL8/NAP1 form V;IL-8 (9-77);GCP/IL-8 protein III;IL8/NAP1 form VI;CXCL8;IL8;
Tissue Specificity	Widely distributed in various tissues.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P10145
Gene Id	3576
Gene Name	CXCL8
Sequence	Contains 1 HMG box DNA-binding domain.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat ELISA, 0.1-0.5ug/ml, -

Reference	1. "Entrez Gene: IL8 interleukin 8". 2. Köhidai L, Csaba G (July 1998). "Chemotaxis and chemotactic selection induced with cytokines (IL-8, RANTES and TNF-alpha) in the unicellular Tetrahymena pyriformis". 3. Modi WS, Dean M, Seuanez HN, Mukaida N, Matsushima K, O'Brien SJ (January 1990). "Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8) resides in a gene cluster along with several other members of the platelet factor 4 gene superfamily". 4. O'Donovan, N., Galvin, M., Morgan, J. G. Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. 5. Utgaard JO, Jahnsen FL, Bakka A, Brandtzaeg P, Haraldsen G (November 1998). "Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells". 6. Wolff B, Bus AR, Middleton J, Rot A (November 1998). "Endothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodies".

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000523-1	PB9621	100 ug	-	$370		Add to Cart
BHA21000523-2	PB9621-10ug	10 ug	Sample	$99		Add to Cart
BHA21000523-3	PB9621-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000523-4	PB9621-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000523-5	PB9621-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000523-6	PB9621-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000523-7	PB9621-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000523-8	PB9621-FITC	100 ug	FITC	$570		Add to Cart
BHA21000523-9	PB9621-HRP	100 ug	HRP	$570		Add to Cart
BHA21000523-10	PB9621-APC	100 ug	APC	$670		Add to Cart
BHA21000523-11	PB9621-PE	100 ug	PE	$670		Add to Cart
BHA21000523-12	PB9621-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000523-13	PB9621-carrier-free	100 ug	carrier-free	$370		Add to Cart

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