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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL3 Antibody Picoband®

SKU : BHA21003057

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Mfr.No.	A02435, A02435-10ug, A02435-Biotin, A02435-Cy3, A02435-Dylight488, A02435-Dylight550, A02435-Dylight594, A02435-FITC, A02435-HRP, A02435-APC, A02435-PE, A02435-iFluor647, A02435-carrier-free
Alternative Names	PH domain and leucine rich repeat protein phosphatase 1
Background	Interleukin 3, also known as IL-3, is a protein that in humans is encoded by the IL3 gene. It is mapped to 5q31.1. IL-3 is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells or, with the addition of IL-7, into lymphoid progenitor cells. In addition, IL-3 stimulates proliferation of all cells in the myeloid lineage (granulocytes, monocytes, and dendritic cells), in conjunction with other cytokines, e.g., Erythropoietin (EPO), Granulocyte macrophage colony-stimulating factor (GM-CSF), and IL-6. IL-3 is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-IL3 Antibody Picoband® catalog # A02435. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on 'Ser-473' of AKT2 and AKT3, 'Ser-660' of P
Host	Rabbit
Immunogen Region	E.coli-derived mouse IL3 recombinant protein (Position: E91-C166).
Isotype	Rabbit IgG
Molecular Weight	26 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	PH domain leucine-rich repeat-containing protein phosphatase 1; Pleckstrin homology domain-containing family E member 1; PH domain-containing family E member 1; Suprachiasmatic nucleus circadian oscillatory protein; hSCOP; PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP
Tissue Specificity	Monocyte/macrophage specific.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.005mg NaN3.

Uniprot	P01586
Gene Id	16187
Gene Name	Il3
Subcellular Location	Nucleus. Cytoplasm. Membrane. Peripheral membrane protein. Cell membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Mouse<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Mouse<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Yang YC, Ciarletta AB, Temple PA, Chung MP, Kovacic S, Witek-Giannotti JS, Leary AC, Kriz R, Donahue RE, Wong GG (October 1986). "Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3". Cell 47 (1): 310.<br /><br />2. Webb, G. C., Lee, J. S., Campbell, H. D., Young, I. G. The genes for interleukins 3 and 5 map to the same locus on mouse chromosome 11. Cytogenet. Cell Genet. 50: 107-110, 1989.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003057-1	A02435	-	100 ug	$370		Add to Cart
BHA21003057-2	A02435-10ug	Sample	10 ug	$99		Add to Cart
BHA21003057-3	A02435-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003057-4	A02435-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003057-5	A02435-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003057-6	A02435-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003057-7	A02435-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003057-8	A02435-FITC	FITC	100 ug	$570		Add to Cart
BHA21003057-9	A02435-HRP	HRP	100 ug	$570		Add to Cart
BHA21003057-10	A02435-APC	APC	100 ug	$670		Add to Cart
BHA21003057-11	A02435-PE	PE	100 ug	$670		Add to Cart
BHA21003057-12	A02435-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003057-13	A02435-carrier-free	carrier-free	100 ug	$370		Add to Cart

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