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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL1RA/Il1rn Antibody Picoband®

SKU : BHA21003290

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Mfr.No.	A00651-5, A00651-5-10ug, A00651-5-Biotin, A00651-5-Cy3, A00651-5-Dylight488, A00651-5-Dylight550, A00651-5-Dylight594, A00651-5-FITC, A00651-5-HRP, A00651-5-APC, A00651-5-PE, A00651-5-iFluor647, A00651-5-carrier-free
Alternative Names	Interleukin-1 receptor antagonist protein
Background	The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alteatively spliced transcript variants encoding distinct isoforms have been reported.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-IL1RA/Il1 Antibody Picoband® catalog # A00651-5. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity (By similarity). .
Host	Rabbit
Immunogen Region	E.coli-derived mouse IL1RA/Il1 recombinant protein (Position: K35-Q178).
Isotype	Rabbit IgG
Molecular Weight	18 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Interleukin-1 receptor antagonist protein;IL-1RN;IL-1ra;IRAP;IL1 inhibitor;Il1;Il-1ra;
Tissue Specificity	The intracellular form of IL1RN is predominantly expressed in epithelial cells.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Uniprot	P25085
Gene Id	16181
Gene Name	Il1
Subcellular Location	Secreted .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Mouse, Rat<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. "Entrez Gene: IL1RN interleukin 1 receptor antagonist".<br /><br />2. Patterson D, Jones C, Hart I, Bleskan J, Berger R, Geyer D, Eisenberg SP, Smith MF, Arend WP (January 1993). "The human interleukin-1 receptor antagonist (IL1RN) gene is located in the chromosome 2q14 region". Genomics. 15 (1): 1736.<br /><br />3. Steinkasserer A, Spurr NK, Cox S, Jeggo P, Sim RB (July 1992). "The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci". Genomics. 13(3): 6547.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003290-1	A00651-5	-	100 ug	$370		Add to Cart
BHA21003290-2	A00651-5-10ug	Sample	10 ug	$99		Add to Cart
BHA21003290-3	A00651-5-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003290-4	A00651-5-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003290-5	A00651-5-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003290-6	A00651-5-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003290-7	A00651-5-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003290-8	A00651-5-FITC	FITC	100 ug	$570		Add to Cart
BHA21003290-9	A00651-5-HRP	HRP	100 ug	$570		Add to Cart
BHA21003290-10	A00651-5-APC	APC	100 ug	$670		Add to Cart
BHA21003290-11	A00651-5-PE	PE	100 ug	$670		Add to Cart
BHA21003290-12	A00651-5-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003290-13	A00651-5-carrier-free	carrier-free	100 ug	$370		Add to Cart

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