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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL17/IL17A Antibody Picoband®

SKU : BHA21006594

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Mfr.No.	RP1019, RP1019-10ug, RP1019-Biotin, RP1019-Cy3, RP1019-Dylight488, RP1019-Dylight550, RP1019-Dylight594, RP1019-FITC, RP1019-HRP, RP1019-APC, RP1019-PE, RP1019-iFluor647, RP1019-carrier-free
Alternative Names	Interleukin-17A
Background	Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IL17/IL17A Antibody catalog # RP1019. Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Induces stromal cells to produce proinflammatory and hematopoietic cytokines. .
Host	Rabbit
Immunogen Region	E. coli-derived mouse IL-17 recombinant protein (Position: A26-A158).
Isotype	Rabbit IgG
Molecular Weight	30 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-17A;IL-17;IL-17A;Cytotoxic T-lymphocyte-associated antigen 8;CTLA-8;Il17a;Ctla8, Il17;
Tissue Specificity	Restricted to a subset of activated T-cells. .
Note	Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify "Carrier Free" or "No BSA" in your order note.

Uniprot	Q62386
Gene Name	IL17A
Sequence	Belongs to the immunoglobulin superfamily. CEA family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	ELISA, 0.1-0.5ug/ml, -<br>Weste blot, 0.1-0.5ug/ml, Mouse<br>

Reference	1. Harrington, L. E., Hatton, R. D., Mangan, P. R., Tuer, H., Murphy, T. L., Murphy, K. M., Weaver, C. T.Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages.Nature Immun. 6: 1123-1132, 2005.<br /><br />2. Kennedy, J., Rossi, D. L., Zurawski, S. M., Vega, F., Jr.Kastelein, R. A.; Wagner, J. L.; Hannum, C. H.; Zlotnick, A.: Mouse IL-17: a cytokine preferentially expressed by alpha beta TCR + CD4-CD8-T cells.J. Interferon Cytokine Res. 16: 611-617, 1996.<br /><br />3. Kotake, S., Udagawa, N., Takahashi, N., Matsuzaki, K., Itoh, K., Ishiyama, S., Saito, S., Inoue, K., Kamatani, N., Gillespie, M. T., Martin, T. J., Suda, T.IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis.J. Clin. Invest. 103: 1345-1352, 1999.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006594-1	RP1019	-	100 ug	$370		Add to Cart
BHA21006594-2	RP1019-10ug	Sample	10 ug	$99		Add to Cart
BHA21006594-3	RP1019-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006594-4	RP1019-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006594-5	RP1019-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006594-6	RP1019-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006594-7	RP1019-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006594-8	RP1019-FITC	FITC	100 ug	$570		Add to Cart
BHA21006594-9	RP1019-HRP	HRP	100 ug	$570		Add to Cart
BHA21006594-10	RP1019-APC	APC	100 ug	$670		Add to Cart
BHA21006594-11	RP1019-PE	PE	100 ug	$670		Add to Cart
BHA21006594-12	RP1019-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006594-13	RP1019-carrier-free	carrier-free	100 ug	$370		Add to Cart

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