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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL12 p40/IL12B Antibody Picoband®

SKU : BHA21007497

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Mfr.No.	RP1028, RP1028-10ug, RP1028-Biotin, RP1028-Cy3, RP1028-Dylight488, RP1028-Dylight550, RP1028-Dylight594, RP1028-FITC, RP1028-HRP, RP1028-APC, RP1028-PE, RP1028-iFluor647, RP1028-carrier-free
Alternative Names	Interleukin-12 subunit beta
Background	Subunit beta of interleukin 12, also known as interleukin 12B, or IL12B, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IL12 p40/IL12B Antibody catalog # RP1028. Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. .
Host	Rabbit
Immunogen Region	E.coli-derived rat IL-12 (p40) recombinant protein (Position: M23-S321).
Isotype	Rabbit IgG
Molecular Weight	20 kDa
Reactivity	Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-12 subunit beta ;Cytotoxic lymphocyte maturation factor 40 kDa subunit ;IL-12 subunit p40 ;Il12b ;IL12B ;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q9R278
Gene Id	64546
Gene Name	IL12B
Sequence	Belongs to the type I cytokine receptor family. Type 3 subfamily.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Rat<br>

Reference	1. Entrez Gene: IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)<br /><br />2. Yokouchi, Y., Nukaga, Y., Shibasaki, M., Noguchi, E., Kimura, K., Ito, S., Nishihara, M., Yamakawa-Kobayashi, K., Takeda, K., Imoto, N., Ichikawa, K., Matsui, A., Hamaguchi, H., Arinami, T. Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families. Genomics 66: 152-160, 2000.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007497-1	RP1028	-	100 ug	$370		Add to Cart
BHA21007497-2	RP1028-10ug	Sample	10 ug	$99		Add to Cart
BHA21007497-3	RP1028-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007497-4	RP1028-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007497-5	RP1028-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007497-6	RP1028-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007497-7	RP1028-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007497-8	RP1028-FITC	FITC	100 ug	$570		Add to Cart
BHA21007497-9	RP1028-HRP	HRP	100 ug	$570		Add to Cart
BHA21007497-10	RP1028-APC	APC	100 ug	$670		Add to Cart
BHA21007497-11	RP1028-PE	PE	100 ug	$670		Add to Cart
BHA21007497-12	RP1028-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007497-13	RP1028-carrier-free	carrier-free	100 ug	$370		Add to Cart

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